• Publications
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Analysis of the complete nucleotide sequence of African swine fever virus.
TLDR
Analysis of the complete genome of African swine fever virus (ASFV) strain BA71V confirms the intermediate characteristics of ASFV between poxviruses and iridoviruses, supporting the notion that AsFV belongs to an independent virus family. Expand
Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels.
Titration of African swine fever (ASF) virus.
TLDR
A plaque assay for ASF virus adapted to grow in VERO cells gives a titre similar to that obtained using the haemadsorption microtest, and in both the micromethod and the plaque assay infection may be produced by a single infective particle. Expand
African swine fever virus encodes a CD2 homolog responsible for the adhesion of erythrocytes to infected cells
TLDR
This result demonstrates that the protein encoded by EP402R is directly involved in the hemadsorption phenomenon induced by the infection of susceptible cells with African swine fever virus. Expand
Inducible Gene Expression from African Swine Fever Virus Recombinants: Analysis of the Major Capsid Protein p72
TLDR
The results of this report demonstrate that the transferred inducible expression system is a powerful tool for analyzing the function of ASFV genes. Expand
African swine fever virus.
  • E. Viñuela
  • Biology, Medicine
  • Current topics in microbiology and immunology
  • 1985
African swine fever (ASF) was first described in 1921 by Montgomery, who reported several disease outbreaks of domestic pigs in Kenya since 1910 with a mortality close to 100%. Montgomery recognizedExpand
African Swine Fever Virus Is Enveloped by a Two-Membraned Collapsed Cisterna Derived from the Endoplasmic Reticulum
TLDR
Results indicate that ASFV, like the poxviruses, becomes engulfed by a two-membraned collapsed cisterna derived from the ER. Expand
Inhibition of nuclear factor kappaB activation by a virus-encoded IkappaB-like protein.
TLDR
Results indicate that the African swine fever virus IkappaB gene homologue interferes with NF-kappaB activation, likely representing a new mechanism to evade the immune response during viral infection. Expand
Purification and properties of African swine fever virus
We describe a method for African swine fever (ASF) virus purification based on equilibrium centrifugation in Percoll density gradients of extracellular virions produced in infected VERO cells thatExpand
Inhibition of apoptosis by the African swine fever virus Bcl-2 homologue: role of the BH1 domain.
TLDR
It was found that the Gly-to-Ala mutation in the BH1 domain of the viral protein abolished its capacity to protect the K562 cells from apoptosis, indicating that this Gly is essential for A179L action. Expand
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