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A preliminary study for the production of high specific activity radionuclides for nuclear medicine obtained with the isotope separation on line technique.
Stable ion beams of strontium, yttrium and iodine were produced using the SPES test bench (Front-End) to simulate the production of 89Sr, 90Y, 125I and 131I and collected with good efficiency on suitable targets. Expand
Application of the National Early Warning Score (NEWS) as a stratification tool on admission in an Italian acute medical ward: A perspective study
We aimed to assess the performance of the National Early Warning Score (NEWS) as tool for patient risk stratification at admission in an acute Internal Medicine ward and to ensure patient placementExpand
Ethosomes for Dermal Administration of Natural Active Molecules.
This review focuses on work carried out in vitro, in vivo in animal models and in humans in clinical studies, with ethosomal formulations containing natural active molecules for the treatment of skin disorders, with examples of disorders managed successfully by ethosomal systems. Expand
The ISOLPHARM project: A New ISOL production method of high specific activity beta-emitting radionuclides as radiopharmaceutical precursors
The ISOLPHARM project explores the feasibility of exploiting an innovative technology to produce extremely high specific activity beta-emitting radionuclides as radiopharmaceutical precursors. This...
Higher heparin dosages reduce thromboembolic complications in patients with COVID-19 pneumonia
Different enoxaparin doses/kg of body weight in the prevention of clot complications in COVID-19 pneumonia showed a better thromboprophylactic action, independently from the clinical presentation of the disease, therefore, COVID -19 pneumonia might request higher enoxAParin doses to reduce thromboembolic events in hospitalized patients, even if outside intensive care units. Expand
Preliminary evaluation of the production of non-carrier added 111Ag as core of a therapeutic radiopharmaceutical in the framework of ISOLPHARM_Ag experiment.
The presented work is focused on the first part of the production chain including the capability to extract, ionize, and collect stable Ag beams with SPES technologies, aimed at evaluating the feasibility of theProduction of a111Ag labelled radiopharmaceutical. Expand
Preliminary Study of a 1,5-Benzodiazepine-Derivative Labelled with Indium-111 for CCK-2 Receptor Targeting
In this study, a nastorazepide-based ligand functionalized with a 1,4,7,10-tetraazacyclododecane-1, 4, 7, 10-Tetraacetic acid (DOTA) chelator (IP-001) was synthesized and labelled with indium-111, a suitable target for developing specific radiotracers for cholecystokinin-2 receptor overexpressed cancers. Expand
ISOLPHARM , a new production method of high specific activity beta-emitting radionuclides as radiopharmaceutical precursors
At INFN-LNL (Istituto Nazionale di Fisica Nucleare– Laboratori Nazionali di Legnaro) SPES (Selective Production of Exotic Species), a new facility for the production of radioactive ion beams is beingExpand