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Normal and keloid fibroblasts are differentially influenced by IFN‐γ and triamcinolone as well as by their combination
Impaired wound healing as well as imbalanced cell proliferation and extracellular matrix synthesis and degeneration can cause aberrant scarring. The most severe impacts of such scarring on patients'Expand
Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany
Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialisedExpand
Dimethyl fumarate – only an anti‐psoriatic medication?
Fumaric acid esters have been used successfully in the therapy of psoriasis vulgaris since 1959. In the last 17 years, many of the underlying mechanisms of anti‐psoriatic action, such as a Th1/Th2Expand
Dimethylfumarate inhibits melanoma cell proliferation via p21 and p53 induction and bcl-2 and cyclin B1 downregulation
Recent evidence suggests that dimethylfumarate (DMF), known as a highly potent anti-psoriatic agent, might have anti-tumorigenic properties in melanoma. It has recently been demonstrated that DMFExpand
Human leucocyte antigen class I and class II antigen expression in malignant fibrous histiocytoma, fibrosarcoma and dermatofibrosarcoma protuberans is significantly downregulated
Background  Abnormalities in the expression of human leucocyte antigens (HLA) by tumour cells impair cellular immune responses promoting immune evasion and tumour survival. To date, studies analysingExpand
Frontal fibrosing alopecia – review of recent case reports and case series in PubMed
In his initial publication of frontal fibrosing alopecia (FFA) in 1994, Steven Kossard included six postmenopausal women. A type of cicatricial alopecia, FFA is clinically characterized byExpand
Use of specific immunotherapy – a survey of 15 164 employed persons in Germany
The high prevalence of allergic rhinitis (AR) leads to high morbidity and costs. Specific immunotherapy (SIT) is a potentially curative therapy for AR. The decision whether or not to employ SIT isExpand
Directing adipose‐derived stem cells into keratinocyte‐like cells: impact of medium composition and culture condition
Adipose‐derived stem cells (ASC) are known to transdifferentiate into a wide range of different cell species in vitro including along the epidermal lineage. This property makes them a promising toolExpand
Loss of interferon‐γ inducibility of the MHC class II antigen processing pathway in head and neck cancer: evidence for post‐transcriptional as well as epigenetic regulation
Background  Abnormalities of the major histocompatibility complex (MHC) antigens by tumour cells impair the cellular immune response and promote tumour evasion from immune surveillance. So far,Expand
Successful Treatment of Acrodermatitis Continua of Hallopeau with Sequential Combination of Calcipotriol and Tacrolimus Ointments
Acrodermatitis continua of Hallopeau (ACH) is a rare type of pustular psoriasis affecting the digits. We report on a 43-year-old female patient who had been suffering from ACH for more than 20 years.Expand