• Publications
  • Influence
Specific high affinity binding of human interleukin 1β by Caf1A usher protein of Yersinia pestis
Understanding the interaction of Yersinia pestis with the key components of the immune system is important for elucidation of the pathogenesis of bubonic plague, one of the most severe and acuteExpand
Study of interaction between L-glutamate and human blood lymphocytes.
The presence of specific glutamate receptors on T lymphocytes separated from normal human blood was investigated. Upon study of T lymphocytes interaction with [3H]glutamate the last one was found toExpand
Synthesis and properties of the peptide corresponding to the ACTH-like sequence of human immunoglobulin G1.
The decapeptide Val-Lys-Lys-Pro-Gly--Ser-Ser-Val-Lys-Val (termed immunocorticotropin) corresponding to the sequence 11-20 of the variable part of the human immunoglobulin G1 heavy chain wasExpand
The octapeptide corresponding to the region of the highest homology between α‐interferon and thymosin‐α1 effectively competes with both cytokines for common high‐affinity receptors on murine
The octapeptide corresponding to human interferon‐α2 (Hu IFN‐α2) sequence 131–138 hu??? high affinity to murine thymocyte receptors (K 6 = 4.2 × 10−11 M, about 700 receptors per cell). TheExpand
Synthetic ACTH-Like Peptide GKVLKKRR, Corresponding to the Fragment 81–88 of Human Pro-Interleukin-1α, Acts as an Antagonist of ACTH Receptor
Synthetic adrenocorticotropic hormone (ACTH)-like octapeptide leukocorticotropin (GKVLKKRR), corresponding to the amino acid sequence 81–88 of pro-interleukin-1α, was labeled with tritium (specificExpand
Binding of cholera toxin B subunit to intestinal epithelial cells.
We have prepared 125I-labeled cholera toxin B subunit (125I-labeled CT-B, a specific activity of 98Ci/mmol) and found that it binds to rat IEC-6 and human Caco-2 intestinal epithelial cells with highExpand
Synthetic peptide octarphin (TPLVTLFK), a selective agonist of nonopioid β‐endorphin receptor, stimulates nitric oxide synthesis in macrophages
Synthetic peptide octarphin (TPLVTLFK, a selective agonist of nonopioid β‐endorphin receptor) was able to activate in a dose‐dependent manner murine macrophages to express nitric oxide (NO) synthaseExpand
Effect of the B Subunit of the Cholera Toxin on the Raw 264.7 Murine Macrophage-Like Cell Line
The 125I-labeled B-subunit of the cholera toxin ([125I]CT-B with specific activity 98 Ci/mmol) was found to be bonded to the murine macrophage-like cells of the RAW 264.7 line with high affinity (KdExpand
Interaction of Cholera Toxin B Subunit with Rat Intestinal Epithelial Cells
We prepared 125I-labeled cholera toxin B subunit (125I-labeled CT-B, specific activity 98 Ci/mmol) and found that its binding to rat IEC-6 intestinal epithelial cells was high-affinity (Kd 1.9 nM).Expand
Receptor-binding properties of the peptides corresponding to the beta-endorphin-like sequence of human immunoglobulin G.
The decapeptide H2N-Ser-Leu-Thr-Cys-Leu-Val-Lys-Gly-Phe-Tyr-COOH (termed immunorphin) corresponding to the sequence 364-373 of the CH3 domain of the human immunoglobulin G1 Eu heavy chain andExpand