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Upregulation of Endogenous Erythropoietin (EPO) in Healthy Subjects by Inhibition of Hypoxia Inducible Factor (HIF) Prolyl Hydroxylase.
The data provide first proof of concept for upregulation of endogenous EPO and erythropoietic responses in humans by a specific HIF-PH inhibitor.
Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agents.
Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents.
Design and synthesis of procollagen C-proteinase inhibitors.
Structure stability/activity relationships of sulfone stabilized N,N-dichloroamines.
Inhibition of procollagen C-proteinase: fibrosis and beyond
This review provides a discussion of the therapeutic potential of PCP inhibition and an examination of relevant patent literature, primarily focused on the identification of small molecule inhibitors ofPCP for the prevention of dermal scarring and fibrotic disease.
Reactivity of ester linkages and pentaammineruthenium(III) at the monolayer assembly/solution interface
The rate of base-mediated ester hydrolysis in monolayers of 11-mercaptoundecyl isonicotinate on gold is monitored by infrared spectroscopy and cyclic voltammetry. The hydrolysis product, a…
Novel N-chloroheterocyclic antimicrobials.
Novel 3-chlorooxazolidin-2-ones as antimicrobial agents.