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Brain and cardiovascular diseases: common neurogenic background of cardiovascular, metabolic and inflammatory diseases.
In spite of significant progress in pharmacotherapy the incidence of newly diagnosed cases of cardiovascular diseases and cardiovascular morbidity is alarmingly high. Treatment of hypertension orExpand
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Hypotensive function of the brain angiotensin-(1-7) in Sprague Dawley and renin transgenic rats.
Angiotensin-(1-7) (Ang-[1-7]) is present in the brain of normotensive Sprague Dawley (SD) rats, and its hypothalamic content is elevated in TGRmRen2(27) rats (TGR) with renin dependent transgenicExpand
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Vasopressin in blood and third ventricle CSF during dehydration, thirst, and hemorrhage.
Samples of cerebrospinal fluid (CSF) were collected from the anterior part of the third cerebral ventricle of mongrel dogs with a chronically implanted device. Repeated experiments with simultaneousExpand
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Evidence that centrally released arginine vasopressin is involved in central pressor action of angiotensin II.
Five series of experiments were performed on conscious trained dogs to find out whether intracranially released arginine vasopressin (AVP) is involved in mediation of central cardiovascular effectsExpand
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TNF and angiotensin type 1 receptors interact in the brain control of blood pressure in heart failure.
UNLABELLED Accumulating evidence suggests that the brain renin-angiotensin system and proinflammatory cytokines, such as TNF-α, play a key role in the neurohormonal activation in chronic heartExpand
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Mechanisms of Hypovolaemic Thirst and Interactions between Hypovolaemia, Hyperosmolality and the Antidiuretic System
The proposal that changes in plasma osmolality determine thirst was made first by Mayer (1900). It remained for Gilman (1937) to show that cellular dehydration, brought about by an increase in theExpand
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Central dipsogenic effect of vasopressin.
The purpose of the present study was to investigate the possible role of vasopressin (ADH) in the control of thirst. With this aim spontaneous water intake (WI) was examined in conscious dogs afterExpand
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Interaction of vasopressin and angiotensin II in central control of blood pressure and thirst
It is now well recognized that systemically released angiotensin II (Ang II) and arginine vasopressin (AVP) act in concert in regulation of blood pressure and water-electrolyte balance. NumerousExpand
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Central ANP attenuates pressor responses to central AVP in WKY and SHR
Blood pressure and heart rate responses to intracerebroventricular (ICV) injections of atrial natriuretic peptide (ANP, 125 ng) arginine vasopressin (AVP, 10 ng), combination of ANP (125 ng) and AVPExpand
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Enhanced involvement of brain vasopressin V1 receptors in cardiovascular responses to stress in rats with myocardial infarction
Stress is one of the factors provoking cardiovascular complications. The purpose of the study was to explore the role of vasopressin (VP) in central control of arterial blood pressure and heart rateExpand
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