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Clinicopathologic Features and Long-term Outcomes of NUT Midline Carcinoma
NMC portends a poor prognosis among all squamous cell neoplasms and seems to be frequently unrecognized; the finding that conventional chemotherapy has been inadequate indicates a pressing need for the development of targeted therapeutics.
Malignancy risk for fine-needle aspiration of thyroid lesions according to the Bethesda System for Reporting Thyroid Cytopathology.
- V. Jo, E. Stelow, Simone M. Dustin, K. Hanley
- MedicineAmerican journal of clinical pathology
- 1 September 2010
Fine-needle aspiration (FNA) is an important test for triaging patients with thyroid nodules. The 2007 National Cancer Institute Thyroid Fine-Needle Aspiration State-of-the-Science Conference helped…
Diagnosis of NUT Midline Carcinoma Using a NUT-specific Monoclonal Antibody
IHC staining with the C52 monoclonal antibody is a highly sensitive and specific test that reliably distinguishes NMC from other forms of carcinoma.
Human Papillomavirus–related Carcinoma With Adenoid Cystic–like Features: A Peculiar Variant of Head and Neck Cancer Restricted to the Sinonasal Tract
These cases draw attention to an unusual variant of HPV-related carcinoma that has a predilection for the sinonasal tract that is histologically similar to adenoid cystic carcinoma (ACC).
A Review of NUT Midline Carcinoma
- E. Stelow
- MedicineHead and neck pathology
- 8 January 2011
The clinicopathologic features ofNut midline carcinomas are reviewed and ancillary testing is discussed as well as the pathologic differential diagnosis.
EWSR1 Genetic Rearrangements in Salivary Gland Tumors: A Specific and Very Common Feature of Hyalinizing Clear Cell Carcinoma
- Akeesha A. Shah, R. Legallo, E. Stelow
- MedicineThe American journal of surgical pathology
- 1 April 2013
Findings show that the EWSR1 rearrangement is almost a defining feature of HCCCs and also confirm that classic salivary gland myoepitheliomas are distinct from these tumors and do not share a pathogenetic relationship with their soft tissue counterparts.
Is Nonsmall Cell Type High-grade Neuroendocrine Carcinoma of the Tubular Gastrointestinal Tract a Distinct Disease Entity?
- J. Shia, Laura H. Tang, D. Klimstra
- Medicine, BiologyThe American journal of surgical pathology
- 1 May 2008
This study demonstrates the existence of both small cell and nonsmall cell types of HGNEC in the GI tract, and provides a detailed illustration of their morphologic spectrum.
Standardized terminology and nomenclature for pancreatobiliary cytology: The Papanicolaou Society of Cytopathology Guidelines
This document selectively presents the results of discussions and focuses on a proposed standardized terminology scheme for pancreatobiliary specimens that correlate cytological diagnosis with biological behavior and increasingly conservative patient management of surveillance only.
Preoperative Capecitabine and Concurrent Radiation for Borderline Resectable Pancreatic Cancer
A neoadjuvant approach to borderline resectable PDA identifies patients who are most likely to benefit from pancreatic resection and preoperative capecitabine-based chemoradiation is an effective, well-tolerated treatment for these patients.
SMARCB1 (INI-1)-deficient Sinonasal Carcinoma: A Series of 39 Cases Expanding the Morphologic and Clinicopathologic Spectrum of a Recently Described Entity
SMARCB1-deficient sinonasal carcinoma represents an emerging poorly differentiated/undifferentiated sin onasal cancer that cannot be better classified as another specific tumor type, has consistent histopathologic findings (albeit with some variability) with varying proportions of plasmacytoid/rhabdoid cells, and demonstrates an aggressive clinical course.