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Sympathogenic origin and antiadrenergic prevention of stress-induced myocardial lesions.
It is concluded that the stress-induced severe myocardial structural lesions in hormone-preconditioned animals are directly attributable to the reflex liberation of potentially cardiotoxic adrenosympathogenic catecholamines which accompanies all stressful situations.
Study of the luteinizing hormone-induced increase of ovarian blood flow during the estrous cycle in the rat.
It was concluded that in LH-induced hyperemia, cAMP, prostaglandins and other vasoactive metabolites released during the process of hormone synthesis, and also a beta-adrenergic mechanism, are involved in the regulation of ovarian blood flow.
Stimulation of progesterone production by adrenocorticotropic hormone and prostaglandin E2 in rat luteal cells.
The effect of ACTH seem to be connected with specific ACTH-binding sites of the luteal cell membrane and with increased production of PGE2, and could be prevented by indomethacin.
CRF-dependent and CRF-independent mechanisms involved in hypophysial-adrenal system activation by bacterial endotoxin.
It is suggested that in response to LPS activation of HPA both CRF(s)-dependent and CRF (s)-independent mechanisms are involved, even a direct effect of the adrenal cortex should be taken into account.
Inhibition of the stimulatory effect of ACTH on adrenal and ovarian blood flow by indomethacin in the dog.
Indomethacin, depending on the dose and on the time elapsing after its administration inhibited the enhancing effect of ACTH on adrenal and ovarian blood flow, and it was suggested that prostaglandins act as mediators in the vasodilatation elicited by ACTH in the canine adrenals and ovary.
Effect of ACTH on gonadal blood flow in the golden hamster and the rat.
Abstract As measured with the rubidium e 6 method, ACTH was found to increase both adrenal and ovarian blood flow in the golden hamster, but only adrenal flow in the rat. The hormone had no effect on
Adrenal blood flow response to adrenocorticotrophic hormone and other stimuli in the dog
The rubidium86 method yielded the same results in dogs as those obtained by Sapirstein in rats after ACTH, and hypotension induced by bleeding and vasoconstriction elicited with vasopressin produced less substantial reductions in adrenal than in renal and thyroidal blood flow.
Expression of kinin receptor mRNA in the HPA axis of type 1 and type 2 diabetic rats.
Enhanced pituitary B2 mRNA in type 2 and reduced adrenal in type 1 diabetes account for a differential pattern in release of transmitters and reflect a functional relationship in HPA axis in diabetes.