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Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population.
- M. G. Scordo, A. Caputi, Concetta D'Arrigo, G. Fava, E. Spina
- Biology, MedicinePharmacological research
- 1 August 2004
Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance
- M. G. Scordo, V. Pengo, E. Spina, M. Dahl, M. Gusella, R. Padrini
- Biology, MedicineClinical pharmacology and therapeutics
- 1 December 2002
Our objective was to determine the influence of cytochrome P450 (CYP) 2C9 and CYP2C19 genetic polymorphisms on warfarin dose requirement and metabolic clearance.
Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: an update.
- E. Spina, V. Santoro, Concetta D'Arrigo
- Medicine, PsychologyClinical therapeutics
- 1 July 2008
Metabolic drug interactions with newer antipsychotics: a comparative review.
- E. Spina, J. de Leon
- Medicine, PsychologyBasic & clinical pharmacology & toxicology
- 2007
TLDR
Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone
- M. G. Scordo, E. Spina, G. Facciolá, A. Avenoso, I. Johansson, M. Dahl
- MedicinePsychopharmacology
- 1 December 1999
TLDR
CYP2D6 and CYP2C19 genotype‐based dose recommendations for antidepressants:
a first step towards subpopulation‐specific dosages
- J. Kirchheiner, K. Brøsen, J. Brockmöller
- Medicine, BiologyActa psychiatrica Scandinavica
- 1 September 2001
TLDR
Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.
- M. Scordo, E. Aklillu, U. Yasar, M. Dahl, E. Spina, M. Ingelman-Sundberg
- Biology, MedicineBritish journal of clinical pharmacology
- 1 October 2001
TLDR
Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes.
- N. Yasui-Furukori, M. Hidestrand, E. Spina, G. Facciolá, M. Scordo, G. Tybring
- Chemistry, BiologyDrug metabolism and disposition: the biological…
- 1 October 2001
TLDR
Clobazam Therapeutic Drug Monitoring: A Comprehensive Review of the Literature With Proposals to Improve Future Studies
- J. de Leon, E. Spina, F. J. Diaz
- MedicineTherapeutic drug monitoring
- 1 February 2013
TLDR
Relationship between plasma concentrations of clozapine and norclozapine and therapeutic response in patients with schizophrenia resistant to conventional neuroleptics
- E. Spina, A. Avenoso, E. Perucca
- Psychology, MedicinePsychopharmacology
- 2000
TLDR
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