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Modulation of Bleomycin-Induced Lung Fibrosis by Pegylated Hyaluronidase and Dopamine Receptor Antagonist in Mice
Hyaluronidases are groups of enzymes that degrade hyaluronic acid (HA). To stop enzymatic hydrolysis we modified testicular hyaluronidase (HYAL) by activated polyethylene oxide with the help ofExpand
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Catecholamine regulation of stromal precursors and hemopoietic stem cells in cytostatic myelosuppression
Effects of a sympatholytic drug on bone marrow stromal and hemopoietic precursors were studied on the model of cyclophosphamide-induced myelosuppression. Sympatholytic treatment increased the contentExpand
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Adrenergic and cholinergic mechanisms of hemopoiesis regulation during experimental neuroses
Scopolamine abolished hyperplasia of erythropoiesis caused by conflict situation and its inhibition after paradoxical sleep deprivation, but did not affect granulomonocytopoiesis. The modulatoryExpand
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Hemostimualting Properties of Preparation Containing Ultralow Doses of Antibodies to Stem Cell Factor in Cytostatic Myelosuppression
The preparation containing ultralow doses of antibodies to stem cell factor considerably activates bone marrow myelopoiesis suppressed by cyclophosphamide. This effect of the preparation is based onExpand
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Anti-fibrotic Effects of Reserpine on Lung Fibrosis: Stem Cells in the Pathogenesis of Pneumofibrosis
In this study was found that inflammation in interstitial lung tissue of mice C57Bl/6 after intratracheal injection of the bleomycin is accompanied by the increase of the bone marrow and circulatingExpand
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Responses of erythroid cells to different neurotic influences
Cells of the erythrocytic series develop hyperplasia in mice exposed to immobilization stress, conflict situation, or conflict situation while being deprived of REM sleep. These mice containExpand
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Effects and Mechanisms of Hemopoiesis-Stimulating Activity of Immobilized Oligonucleotides under Conditions of Cytostatic Myelosuppression
Hemopoiesis-stimulating activity of immobilized oligonucleotide preparation was studied on the model of cytostatic myelosuppression induced by injection of cyclophosphamide and 5-fluorouracil.Expand
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Role of Sertoli and Leydig Cells in the Regulation of Spermatogonial Stem Cell and Development of Reproductive Disorders in Male C57Bl/6 Mice with Type 1 Diabetes Mellitus
Course administration streptozotocin to male C57Bl/6 mice induces a complex of symptoms typical of type 1 diabetes mellitus: hyperglycemia and insulin deficiency, focal inflammatory infiltration ofExpand
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Reaction of bone marrow hematopoiesis to the toxic effect of paclitaxel
Intraperitoneal injection of paclitaxel (Mitotax) in a single dose of 40 mg/kg was followed by an increase in the number of mitotic granulocytic and erythroid cells, hypoplasia, and pancytopenia ofExpand
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Monoaminergic Regulation of Hemopoiesis under Extreme Conditions
The role of the adrenergic, dopaminergic, and serotoninergic systems in the regulation of hemopoiesis was evaluated on various models of pathological processes (restraint stress, experimentalExpand
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