The impact of urbanization on tropical mangroves (Fortaleza, Brazil): evidence from PAH distribution in sediments.
In vitro and in vivo antitumor effect of 5‐FU combined with piplartine and piperine
Piplartine may enhance the therapeutic effectiveness of chemotherapeutic drugs, and moreover, this combination could improve immunocompetence hampered by 5‐FU, according to the findings.
Removal of some polycyclic aromatic hydrocarbons from petrochemical wastewater using low-cost adsorbents of natural origin.
Induction of apoptosis by pterocarpans from Platymiscium floribundum in HL-60 human leukemia cells.
Overview of the therapeutic potential of piplartine (piperlongumine).
Determination of carbonyl compounds in air and cancer risk assessment in an academic institute in Fortaleza, Brazil
Gastroprotective mechanisms of centipedic acid, a natural diterpene from Egletes viscosa LESS.
The data suggest that CPA affords gastroprotection by different and complementary mechanisms, which include a sparing effect on NP-SH reserve, and roles for endogenous prostaglandins, nitric oxide, and TRPV1-receptor and K(+)(ATP) channel activation.
In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper.
- D. Bezerra, F. Castro, L. Costa-Lotufo
- Biology, ChemistryBrazilian journal of medical and biological…
- 1 June 2006
Histopathological and morphological analyses of the tumor and the organs, including liver, spleen, and kidney, were performed in order to evaluate the toxicological aspects of the treatment with these amides and it was shown that both organs were reversibly affected by piplartine and piperine treatment, but in a different way.
The cytotoxic and embryotoxic effects of kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin.