• Publications
  • Influence
Arsenic exposure and prevalence of type 2 diabetes in US adults.
TLDR
Total urine arsenic was associated with increased prevalence of type 2 diabetes, and this finding supports the hypothesis that low levels of exposure to inorganic arsenic in drinking water, a widespread exposure worldwide, may play a role in diabetes prevalence. Expand
Blood cadmium and lead and chronic kidney disease in US adults: a joint analysis.
TLDR
Findings support consideration of cadmium and lead as chronic kidney disease risk factors in the general population and provide novel evidence of risk with environmental exposure to both metals. Expand
Blood lead below 0.48 micromol/L (10 microg/dL) and mortality among US adults.
TLDR
Despite the marked decrease in blood lead levels over the past 3 decades, environmental lead exposures remain a significant determinant of cardiovascular mortality in the general population, constituting a major public health problem. Expand
Industrial food animal production, antimicrobial resistance, and human health.
TLDR
This review focuses on agricultural antimicrobial drug use as a major driver of antimicrobial resistance worldwide for four reasons: It is the largest use of antimicrobials worldwide; much of the use in agriculture results in subtherapeutic exposures of bacteria; drugs of every important clinical class are utilized in agriculture; and human populations are exposed to antimicrobial-resistant pathogens via consumption of animal products as well as through widespread release into the environment. Expand
Lead Exposure and Cardiovascular Disease—A Systematic Review
TLDR
This systematic review evaluates the evidence on the association between lead exposure and cardiovascular end points in human populations and concludes that the evidence is suggestive but not sufficient to infer a causal relationship of lead exposure with clinical cardiovascular outcomes. Expand
Evaluation of the Association between Arsenic and Diabetes: A National Toxicology Program Workshop Review
TLDR
The evidence is insufficient to conclude that arsenic is associated with diabetes in lower exposure in populations with relatively high exposure levels, although recent studies with better measures of outcome and exposure support an association. Expand
The Microbiome
  • E. Silbergeld
  • Biology, Medicine
  • Toxicologic pathology
  • 1 January 2017
The microbiome is increasingly recognized as a critical component in human development, health, and disease. Its relevance to toxicology and pharmacology involves challenges to current conceptsExpand
Blood lead levels and mortality.
TLDR
Individuals with blood lead levels of 20 to 29 micro g/dL in 1976 to 1980 (15% of the US population at that time) experienced significantly increased all-cause, circulatory, and cardiovascular mortality from 1976 through 1992, and it is strongly encouraged to reduce lead exposure for occupationally exposed workers. Expand
Arsenic exposure and cardiovascular disease: a systematic review of the epidemiologic evidence.
TLDR
A systematic review of the epidemiologic evidence on the association between arsenic and cardiovascular outcomes in Taiwan found limited interpretation of the moderate-to-strong associations between high arsenic exposure and cardiovascular outcome in Taiwan. Expand
Blood Lead Below 0.48 &mgr;mol/L (10 &mgr;g/dL) and Mortality Among US Adults
TLDR
Despite the marked decrease in blood lead levels over the past 3 decades, environmental lead exposures remain a significant determinant of cardiovascular mortality in the general population, constituting a major public health problem. Expand
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