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Ki-67, Cyclin E, and p16 INK4 Are Complimentary Surrogate Biomarkers for Human Papilloma Virus-Related Cervical Neoplasia
Prior studies of Ki-67, cyclin E, and p16 expression have suggested that these biomarkers may be preferentially expressed in cervical neoplasia. This study examined and compared the distribution ofExpand
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Stratified Mucin-Producing Intraepithelial Lesions of the Cervix: Adenosquamous or Columnar Cell Neoplasia?
  • J. Park, D. Sun, +5 authors C. Crum
  • Biology, Medicine
  • The American journal of surgical pathology
  • 1 October 2000
BACKGROUND: Squamous (CIN) and glandular (ACIS) intraepithelial lesions often coexist in the same cervical specimen. However, a less common and little studied variant consists of a stratifiedExpand
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Regional Influences on FOMC Voting Patterns
This paper looks at the monetary policy decisions of the U.S. Federal Reserve and asks whether observed voting patterns have been driven entirely by national concerns, or whether regional factorsExpand
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Trimodal spectroscopy for the detection and characterization of cervical precancers in vivo.
OBJECTIVE The objective of this study was to assess the potential of 3 spectroscopic techniques (intrinsic fluorescence, diffuse reflectance, and light scattering) individually and in combinationExpand
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NAD(P)H and collagen as in vivo quantitative fluorescent biomarkers of epithelial precancerous changes.
During the development of neoplasia, epithelial tissues undergo biochemical and structural changes that can manifest in tissue fluorescence. There have been several reports on different in vivoExpand
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Expression of the p53 homologue p63 in early cervical neoplasia.
BACKGROUND p63, a homologue of the tumor suppressor gene p53, is expressed in embryonic, adult murine, and human basal squamous epithelium and encodes both transactivating and dominant negativeExpand
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Immunotherapy of human cervical high-grade cervical intraepithelial neoplasia with microparticle-delivered human papillomavirus 16 E7 plasmid DNA.
OBJECTIVE The purpose of this study was to evaluate the safety of the administration of a bacterial expression plasmid encoding a 13 amino acid sequence that is highly homologous with humanExpand
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Multimodality therapy in early-stage neuroendocrine carcinoma of the uterine cervix.
OBJECTIVE Patients with early-stage neuroendocrine cervical carcinoma (NECC) have a high mortality rate despite aggressive therapy. The rarity of this tumor precludes initiation of a randomized,Expand
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Conservative management of adenocarcinoma in situ of the cervix.
OBJECTIVE The purpose of this study was to determine the method of treatment and outcome of women with cervical adenocarcinoma in situ (AIS). METHODS Following institutional review board approval,Expand
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Adenoid basal carcinomas of the cervix: a unique morphological evolution with cell cycle correlates.
Adenoid basal carcinoma (ABC) is a rare cervical carcinoma of postmenopausal women composed of small basal-type (basaloid) cells with focal endocervical ("adenoid") differentiation. ABCs areExpand
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