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Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study.
Findings are compatible with modest to moderate effects of sleep-disordered breathing on heterogeneous manifestations of CVD within a range of AHI values that are considered normal or only mildly elevated. Expand
Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study.
A significant proportion of occult SDB in the general population would be missed if screening or case finding were based solely on increased body habitus or male sex, particularly in older adults. Expand
Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in
These observational findings suggest a beneficial effect of whole-grain and fruit and vegetable consumption on the risks of total mortality and incident CAD but not on the risk of ischemic stroke. Expand
Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study.
It is postulate that the prevalence of nocturnal cardiac arrhythmias is higher among subjects with than without sleep-disordered breathing, and individuals with severe sleep- disordered breathing have two- to fourfold higher odds of complex arrhythmia development even after adjustment for potential confounders. Expand
Neighborhood environments and coronary heart disease: a multilevel analysis.
Living in deprived neighborhoods was associated with increased prevalence of coronary heart disease and increased levels of risk factors, with associations generally persisting after adjustment for individual-level variables. Expand
Prospective Study of Obstructive Sleep Apnea and Incident Coronary Heart Disease and Heart Failure: The Sleep Heart Health Study
Obstructive sleep apnea is associated with an increased risk of incident heart failure in community-dwelling middle-aged and older men; its association with incident coronary heart disease in this sample is equivocal. Expand
Sleep-Disordered Breathing and Mortality: A Prospective Cohort Study
In a cohort of 6,441 volunteers followed over an average of 8.2 years, Naresh Punjabi and colleagues find sleep-disordered breathing to be independently associated with mortality and identifyExpand
Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study.
The results of this study suggest that sleep-disordered breathing is independently associated with glucose intolerance and insulin resistance and may lead to type 2 diabetes mellitus. Expand
Percent emphysema, airflow obstruction, and impaired left ventricular filling.
In a population-based study, a greater extent of emphysema on CT scanning and more severe airflow obstruction were linearly related to impaired left ventricular filling, reduced stroke volume, and lower cardiac output without changes in the ejection fraction. Expand
Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study.
The findings from the largest cross-sectional study to date indicate that SDB is associated with systemic hypertension in middle-aged and older individuals of different sexes and ethnic backgrounds. Expand