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Motilin receptor expression in smooth muscle, myenteric plexus, and mucosa of human inflamed and noninflamed intestine
TLDR
The motilin receptor is expressed in human colonic and ileal smooth muscle and was found in the mucosa, which was even higher than in the muscle in IBD tissue. Expand
Effect of hyperglycemia on gastric acid secretion and gastrin release induced by intravenous amino acids.
TLDR
It is concluded that IVAAs stimulate gastric acid secretion, and gastrin and PP release; acute hyperglycemia reduces IVAA-stimulated acid output, and gastroenterological hormone secretion; and circulating nutrients influence gastric Acid and gastrointestinal hormone secretion. Expand
Gastrin releasing peptide receptor expression is decreased in patients with Crohn’s disease but not in ulcerative colitis
TLDR
Only the GRP receptor is expressed in human intestine; expression is highest in longitudinal muscle and myenteric plexus of the colon. Expand
Substance P receptor expression in patients with inflammatory bowel disease Determination by three different techniques, i.e., storage phosphor autoradiography, RT-PCR and immunohistochemistry
TLDR
The quantity of SP binding was significantly increased in the inflamed mucosa of IBD patients, while the mRNA level was not increased, suggesting that SP receptors are a potential target for therapeutic regulation of the inflammatory response. Expand
Serum gastrin and mucosal somatostatin in Helicobacter pylori-associated gastritis.
TLDR
The results suggest that hypergastrinemia in H. pylori gastritis is not caused by antral gastritis and antral somatostatin deficiency alone but that corpus inflammation plays a key role in the origin of hypergastsRinemia. Expand
Effect of hyperglycemia on gastric acid secretion during the gastric phase of digestion.
TLDR
Gastric acid secretion under unstimulated conditions and during the gastric phase of digestion is reduced during hyperglycemia, pointing to impaired vagal cholinergic tone; meal-stimulated gastrin release is significantly reduced; the reduction in meal- Stimulated acid output is correlated with the reduced in gastrin releases; and pancreatic polypeptide secretion is significantly reducing during hyper glycemia. Expand
Medium chain triglycerides activate distal but not proximal gut hormones.
TLDR
The results suggest that MCTs are not rapidly absorbed in the proximal gut but probably reach the ileocolonic region and stimulate PYY release. Expand
Effect of acute hyperglycaemia on basal and fat-induced exocrine pancreatic secretion in humans.
TLDR
It is concluded that basal and fat-stimulated pancreatico-biliary secretion are significantly reduced during acute hyperglycaemia and does not affect intrajejunal fat- Stimulated cholecystokinin secretion. Expand
Effect of Acute Hyperglycemia on Basal and Bombesin‐Stimulated Pancreaticobiliary Secretion in Humans
TLDR
It is concluded that acute hyperglycemia reduces basal but does not affect bombesin-induced pancreaticobiliary secretion. Expand