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Primary and secondary intralymphatic histiocytosis.
BACKGROUND Intralymphatic histiocytosis (IH) is a rare condition often associated with systemic disease. A benign condition, clinical presentations can vary greatly and its cause is largely unknown.Expand
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For personal use. Only reproduce with permission from The Lancet Publishing Group.
A 58-year-old woman was referred by her general practitioner, in December, 1999, with a 3-month history of rapidly progressing symmetrical contraction of the fingers of both hands, which beganExpand
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The spectrum of spitzoid tumours: A clinical study
This study explores the relationship between different types of spitzoid tumours, spindle cell naevus of Reed and spitzoid melanomas. Clinical and histopathological data were retrospectively reviewedExpand
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The DILfrequency study is an adaptive trial to identify optimal IL-2 dosing in patients with type 1 diabetes.
BACKGROUND Type 1 diabetes (T1D) results from loss of immune regulation, leading to the development of autoimmunity to pancreatic β cells, involving autoreactive T effector cells (Teffs). Tregs,Expand
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Management of periocular basal cell carcinoma by Mohs micrographic surgery
Background/aims: To determine the success of Mohs micrographic surgery (MMS) for periocular basal cell carcinoma (BCC) at a tertiary referral centre in the UK. Design: A retrospective interventionalExpand
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Sweat duct proliferation associated with aggregates of elastic tissue and atrophodermia vermiculata: a simulator of microcystic adnexal carcinoma. Report of two cases †
Microcystic adnexal carcinoma (MAC) is a rare, usually solitary, slowly growing, yet aggressive neoplasm with a tendency for local recurrences. Herein, we present two patients who had beenExpand
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Campylobacter gastroenteritis associated with Sweet's syndrome.
Sweet's syndrome or acute febrile neutrophilic dermatosis has been associated with underlying infection, malignancy, inflammatory disease and certain medications. The infection agents associated withExpand
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Targeting regulatory T cells with Interleukin-2 treatment in type 1 diabetes: a response-adaptive, non-randomised, open-label trial of repeat doses of Aldesleukin (DILfrequency)
Background Type 1 diabetes (T1D) results from loss of immune regulation leading to the development of autoimmunity to pancreatic beta-cells, involving autoreactive T effector cells (Teffs).Expand
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Pseudoxanthoma elasticum presenting without typical skin changes
We present a patient who was diagnosed with angioid streaks without typical signs of pseudoxanthoma elasticum (PXE); however, a biopsy from the skin of the neck showed abnormal calcified elasticExpand