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Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.
CONTEXT Plasma fibrinogen levels may be associated with the risk of coronary heart disease (CHD) and stroke. OBJECTIVE To assess the relationships of fibrinogen levels with risk of major vascularExpand
Prevalence and risk factors associated with the metabolic syndrome and dyslipidemia in White, Black, Amerindian and Mixed Hispanics in Zulia State, Venezuela.
TLDR
It is suggested that MS is found in approximately one-third of the Venezuelan adult population in Zulia State, with higher prevalence in men related to the presence of dyslipidemia, and lifestyle interventions in MS subjects are needed in Venezuela to halt the burden of CV disease and diabetes. Expand
Molecular characteristics of liver acetyl CoA carboxylase.
Lean adolescents with increased risk for metabolic syndrome.
TLDR
It is concluded that even with a BMI as low as 21 kg/m2 an inappropriate diet and low physical activity might be responsible for the high insulin levels and dislipidemias in adolescents. Expand
Biochemical changes in cultured foetal rat liver explants.
TLDR
The observations suggest that under the usual culture conditions a minority of the cells retain their functional integrity, not reflected in histologically visible necrosis or cell damage, and the extent of deterioration can be conveniently monitored by the malate dehydrogenase activity released to the medium. Expand
Association of free fatty acids with the insulin-resistant state but not with central obesity in individuals from Venezuela.
TLDR
FFA levels in 47 Venezuelan individuals, men and women, 24-58 years old, were determined and the lack of elements to support the presence of hepatic IR, common to increased visceral lipolysis, might suggest that the IR present in the obese individuals studied, might be due to an increase in subcutaneous fat. Expand
Liver acetyl coenzyme A carboxylase. II. Further molecular characterization.
TLDR
Isocitrate and citrate promote aggregation of the carboxylase to its polymeric form and a 15- to 16-fold activation of catalysis; neither tricarballylate nor Pi has this effect. Expand
LIVER ACETYL COA CARBOXYLASE: THE DISSOCIATION-REASSOCIATION PROCESS AND ITS RELATION TO CATALYTIC ACTIVITY*
TLDR
A more complete physicalchemical characterization of the protomeric and polymeric forms of acetyl CoA carboxylase is provided, as well as an insight into the reversible dissociation-reassociation process and its relation to catalytic activity. Expand
Distribution of mitochondrial enzymes between the perikaryal and synaptic fractions of immature and adult rat brain.
TLDR
The results substantiate previously noted signs of mitochondrial heteroeneity in adult brain, and extend them to immature brain, where the chemical composition, the quantitative pattern of enzymes, of free and synaptic mitochondria is clearly different, and undergoes separate changes during postnatal differentiation. Expand
Collaborative meta-analysis of prospective studies of plasma fibrinogen and cardiovascular disease
TLDR
The Fibrinogen Studies Collaboration will aim to characterize more precisely than has previously been possible the strength and shape of the age- and sex-specific associations of plasma fibr inogen with coronary heart disease and, where data are sufficient, with other vascular diseases. Expand
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