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Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells
TLDR
Evaluated toxicity and potency data suggest that some LRA could potentially activate transcription in latently infected cells in the CNS, and recommend that future trials of LRA also examine the effects of these agents on the CNS via examination of cerebrospinal fluid.
Stage-selective inhibition of rodent malaria by cyclosporine
TLDR
It is indicated that cyclosporine selectively inhibits asexual blood stages of P. berghei and favors the emergence of Csr parasites with diminished infectivity for mosquitoes.
Development of a chemotherapeutic model for microfilaricidal drugs to Dirofilaria immitis.
TLDR
It was shown that after residing in the peripheral circulation the microfilariae were able to develop into infective larvae in mosquitoes; therefore, the system may be a reasonable model of the natural microfilaremic state.
Laboratory transmission of dog heartworm (Dirofilaria immitis) by three species of mosquitoes (Diptera: Culicidae) from eastern Maryland, USA.
TLDR
Three species of mosquitoes from eastern Maryland, USA, were tested for their ability to transmit Dirofilaria immitis (Leidy) from heartworm-positive dogs to recipient dogs with no prior exposure and all 3 test species were found to be capable of transmitting D. immitis to dogs.