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Role of hepatic vein catheterisation and transient elastography in the diagnosis of idiopathic portal hypertension.
BACKGROUND Idiopathic portal hypertension is a rare cause of portal hypertension, frequently misdiagnosed as cryptogenic cirrhosis. This study evaluates specific findings at hepatic veinExpand
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Assessing portal hypertension in liver diseases
Portal hypertension is a common complication of chronic liver diseases and is responsible for most clinical consequences of cirrhosis, which represent the more frequent causes of death and liverExpand
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Von Willebrand factor levels predict clinical outcome in patients with cirrhosis and portal hypertension
Background and aims Endothelial dysfunction is a major determinant of the increased hepatic vascular tone of cirrhotic livers. Von Willebrand factor (vWF), P-selectin and 8-iso-PGF2α (isoprostanes),Expand
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A MELD-based model to determine risk of mortality among patients with acute variceal bleeding.
BACKGROUND & AIMS Patients with cirrhosis with acute variceal bleeding (AVB) have high mortality rates (15%-20%). Previously described models are seldom used to determine prognoses of these patients,Expand
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Bacterial and fungal infections in acute-on-chronic liver failure: prevalence, characteristics and impact on prognosis
Bacterial infection is a frequent trigger of acute-on-chronic liver failure (ACLF), syndrome that could also increase the risk of infection. This investigation evaluated prevalence andExpand
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Assessment of portal hypertension by transient elastography in patients with compensated cirrhosis and potentially resectable liver tumors.
BACKGROUND & AIMS Patients with cirrhosis and small hepatocellular carcinoma with normal bilirubin and hepatic venous pressure gradient (HVPG) <10 mm Hg have >70% 5-year survival after hepaticExpand
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Non-Invasive Diagnostic and Prognostic Evaluation of Liver Cirrhosis and Portal Hypertension
Cirrhosis is the final stage of most of chronic liver diseases, and is almost invariably complicated by portal hypertension, which is the most important cause of morbidity and mortality in theseExpand
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Acute variceal bleeding.
Bleeding from gastroesophageal varices is a frequent complication of cirrhosis. Mortality from a variceal bleeding episode has decreased in the last 2 decades from 40% to 15 to 20% due to theExpand
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Insulin resistance in patients with cirrhosis and portal hypertension.
Insulin resistance (IR) is involved in the pathogenesis of endothelial dysfunction and is also present in patients with cirrhosis. Intrahepatic endothelial dysfunction plays a major role, increasingExpand
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Reliability of the estimation of total hepatic blood flow by Doppler ultrasound in patients with cirrhotic portal hypertension.
BACKGROUND & AIMS Hepatic blood flow (HBF) is best estimated by the Fick's method during indocyanine green constant infusion (ICG-HBF) on hepatic vein catheterization. We investigated the consistencyExpand
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