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Quantitative acoustic measurements for characterization of speech and voice disorders in early untreated Parkinson's disease.
TLDR
It was found that measurement of the fundamental frequency variations applied to two selected tasks was the best method for separating healthy from PD subjects and it has been demonstrated that 78% of early untreated PD subjects indicate some form of vocal impairment.
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Measurement instruments to assess posture, gait, and balance in Parkinson's disease: Critique and recommendations
TLDR
This MDS‐commissioned task force assessed clinimetric properties of existing rating scales, questionnaires, and timed tests that assess features in Parkinson's disease.
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Imprecise vowel articulation as a potential early marker of Parkinson's disease: effect of speaking task.
TLDR
Impaired vowel articulation may be considered as a possible early marker of PD because complex tasks such as monologue are more likely to elicit articulatory deficits in parkinsonian speech, compared to other speaking tasks.
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Survey on cannabis use in Parkinson's disease: Subjective improvement of motor symptoms
An anonymous questionnaire sent to all patients attending the Prague Movement Disorder Centre revealed that 25% of 339 respondents had taken cannabis and 45.9% of these described some form of…
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Evaluation of speech impairment in early stages of Parkinson’s disease: a prospective study with the role of pharmacotherapy
TLDR
Improvements in speech performance can be demonstrated in PD patients after the introduction of antiparkinsonian therapy, and changes in speech articulation and pitch variability appear to be related with dopaminergic responsiveness of bradykinesia and rigidity.
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EFNS/MDS‐ES recommendations for the diagnosis of Parkinson's disease
A Task Force was convened by the EFNS/MDS‐ES Scientist Panel on Parkinson's disease (PD) and other movement disorders to systemically review relevant publications on the diagnosis of PD.
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A new botulinum toxin type A free of complexing proteins for treatment of cervical dystonia
TLDR
A new botulinum toxin type A free of complexing proteins (NT 201) was compared with BOTOX in patients with cervical dystonia by means of a double-blind noninferiority trial and shows that NT 201 is at least as effective and safe as BotoX.
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Selecting deep brain stimulation or infusion therapies in advanced Parkinson’s disease: an evidence-based review
TLDR
A group of experts knowledgeable in all three therapies reviewed the currently available literature for each treatment and identified variables of clinical relevance for choosing one of the three options such as type of motor problems, age, and cognitive and psychiatric status.
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Repetitive TMS of the somatosensory cortex improves writer's cramp and enhances cortical activity.
TLDR
1 Hz rTMS of the SI cortex can improve writer's cramp while increasing the cortical activity in both hemispheres, reflecting the impact of somatosensory system on active motion control.
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Functional magnetic resonance imaging during deep brain stimulation: A pilot study in four patients with Parkinson's disease
TLDR
fMRI during deep brain stimulation is a safe method with considerable potential for elucidating the functional connectivity of the stimulated nuclei and cannot be simply explained by a mechanism of depolarization blockade.
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