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13C NMR spectral and conformational analysis of 8-O-4′ neolignans
Abstract The 13C NMR spectra of the erythro and threo forms of representative members of the 8-O-4′ type of neolignans were recorded and the signals assigned. Based on these assignments and on theExpand
Lignans of Araucaria angustifolia and 13C NMR analysis of some phenyltetralin lignans
Abstract Secoisolariciresinol monomethyl ether and lariciresinol-4-methyl ether were isolated from the knots of dead trees of Araucaria angustifolia . On the basis of spectral evidence, the positionExpand
Pharmacological Characterization of 6-Bromo-3′-nitroflavone, a Synthetic Flavonoid with High Affinity for the Benzodiazepine Receptors
Findings suggest that 6-bromo-3'-nitroflavone has anxiolytic-like action possibly behaving as a partial agonist of the benzodiazepine receptors. Expand
The quest for quinine: those who won the battles and those who won the war.
The recently disclosed syntheses of quinine testify in a remarkable manner the huge progress made by organic synthesis during the last three decades since the first series of partially controlled syntheses by the group of Uskokovic. Expand
Detection of benzodiazepine receptor ligands in small libraries of flavone derivatives synthesized by solution phase combinatorial chemistry.
The solution phase combinatorial synthesis of flavone derivatives and evaluation of their affinity for the central benzodiazepine receptors is described, finding the most promising compounds were 6-bromo-3'-fluoroflavone; 6,3'-dichlor oflavone and 6-chloro- 3'-bromoflavon. Expand
13C NMR analysis of aporphine alkaloids
Abstract The 13 C NMR spectra of some tertiary and quaternary aporphine alkaloids are recorded and the signals assigned. The substituent shielding effects together with the effects of N - and OExpand
Peptide alkaloids of Scutia buxifolia
Abstract From the bark extract of S. buxifolia , the known alkaloids scutianines B, C, D and E, and the new one, scutianine H, have been isolated. The structure of scutianine H, based mainly on itsExpand
13C NMR spectral analysis of lignans from Araucaria angustifolia
Abstract Pinoresinol dimethyl ether, secoisolariciresinol, lariciresinol, isolariciresinol and isolariciresinol-4′-methyl ether were isolated from the knots of dead trees of Araucaria angustifolia .Expand
Peptide alkaloids of Discaria longispina
Abstract Three peptide alkaloids have been isolated from Discaria longispina. They include frangulanine and the new substances discarine A (II) and B (III).