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Inflammation in prostate carcinogenesis
About 20% of all human cancers are caused by chronic infection or chronic inflammatory states. Recently, a new hypothesis has been proposed for prostate carcinogenesis. It proposes that exposure to… Expand
Prevalence of hearing loss and differences by demographic characteristics among US adults: data from the National Health and Nutrition Examination Survey, 1999-2004.
BACKGROUND Hearing loss affects health and quality of life. The prevalence of hearing loss may be growing because of an aging population and increasing noise exposure. However, accurate national… Expand
Prevalence and risk factors for erectile dysfunction in the US.
PURPOSE To assess the prevalence of erectile dysfunction and to quantify associations between putative risk factors and erectile dysfunction in the US adult male population. METHODS Cross-sectional… Expand
Risk factors for prostate cancer incidence and progression in the health professionals follow‐up study
- E. Giovannucci, Yan Liu, E. Platz, M. Stampfer, W. Willett
- International journal of cancer
- 1 October 2007
Risk factors for prostate cancer could differ for various sub‐groups, such as for “aggressive” and “non‐aggressive” cancers or by grade or stage. Determinants of mortality could differ from those for… Expand
Statin drugs and risk of advanced prostate cancer.
- E. Platz, M. Leitzmann, +4 authors E. Giovannucci
- Journal of the National Cancer Institute
- 20 December 2006
BACKGROUND Statins are commonly used cholesterol-lowering drugs that have proapoptotic and antimetastatic activities that could affect cancer risk or progression. Results from previous epidemiologic… Expand
C-reactive protein and the risk of incident colorectal cancer.
CONTEXT Inflammation may play a role in the pathogenesis of colorectal cancer; however, epidemiological evidence supporting this hypothesis in average-risk persons is sparse. OBJECTIVE To determine… Expand
Fruit, vegetable, and antioxidant intake and all-cause, cancer, and cardiovascular disease mortality in a community-dwelling population in Washington County, Maryland.
- J. Genkinger, E. Platz, S. Hoffman, G. Comstock, K. Helzlsouer
- American journal of epidemiology
- 15 December 2004
Higher intake of fruits, vegetables, and antioxidants may help protect against oxidative damage, thus lowering cancer and cardiovascular disease risk. This Washington County, Maryland, prospective… Expand
Obesity, Diabetes, and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial
- Z. Gong, M. Neuhouser, +8 authors A. Kristal
- Cancer Epidemiology Biomarkers & Prevention
- 1 October 2006
Studies on the relationship between obesity and prostate cancer incidence are inconsistent. In part, this inconsistency may be due to a differential effect of obesity on low-grade and high-grade… Expand
Nutritional predictors of insulin-like growth factor I and their relationships to cancer in men.
- E. Giovannucci, M. Pollak, +4 authors W. Willett
- Cancer epidemiology, biomarkers & prevention : a…
- 1 February 2003
The insulin-like growth factor (IGF) axis may play opposing roles in health and disease. The age-related declines in growth hormone and IGF-I may be associated with potentially deleterious changes in… Expand
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer
Objective and methodsThe association of 17 candidate single nucleotide polymorphisms (SNPs) in IL10 and other immune response genes (CRP, TLR4, IL6, IL1B, IL8, TNF, RNASEL) and genes related to… Expand