E. Parkin

Publications15
h-index12
Citations568
Highly Influential Citations25
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Structural variation on the short arm of the human Y chromosome: recurrent multigene deletions encompassing Amelogenin Y.
Structural polymorphism is increasingly recognized as a major form of human genome variation, and is particularly prevalent on the Y chromosome. Assay of the Amelogenin Y gene (AMELY) on Yp is widely… Expand
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Genomic complexity of the Y-STR DYS19: inversions, deletions and founder lineages carrying duplications
The Y-STR DYS19 is firmly established in the repertoire of Y-chromosomal markers used in forensic analysis yet is poorly understood at the molecular level, lying in a complex genomic environment and… Expand
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Dynamic nature of the proximal AZFc region of the human Y chromosome: multiple independent deletion and duplication events revealed by microsatellite analysis
The human Y chromosome shows frequent structural variants, some of which are selectively neutral, while others cause impaired fertility due to the loss of spermatogenic genes. The large‐scale use of… Expand
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Diversity of 26-locus Y-STR haplotypes in a Nepalese population sample: Isolation and drift in the Himalayas
Twenty-six Y-chromosomal short tandem repeat (STR) loci were amplified in a sample of 769 unrelated males from Nepal, using two multiplex polymerase chain reaction (PCR) assays. The 26 loci gave a… Expand
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Within- and between-individual sequence variation among ITS1 copies in the meadow grasshopper Chorthippus parallelus indicates frequent intrachromosomal gene conversion.
Sequencing multiple copies of the ITS1 region revealed the coexistence of two or more haplotypes within the genome of Chorthippus parallelus. Using a PCR-RFLP approach, the ITS1 numbers and… Expand
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26-Locus Y-STR typing in a Bhutanese population sample.
26 Y chromosome short tandem repeat (STR) loci were amplified in a sample of 856 unrelated males from Bhutan, using two multiplex polymerase chain reaction (PCR) assays. The first multiplex is the… Expand
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Gene Conversion Violates the Stepwise Mutation Model for Microsatellites in Y-Chromosomal Palindromic Repeats
The male‐specific region of the human Y chromosome (MSY) contains eight large inverted repeats (palindromes), in which high‐sequence similarity between repeat arms is maintained by gene conversion.… Expand
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Inadvertent diagnosis of male infertility through genealogical DNA testing
2 many companies also offer to deduce ''ancestry''. As the number of markers used in these tests increases, so does the probability of inadvertently diagnosing male infertility through the detec-… Expand
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Africans in Yorkshire? The deepest-rooting clade of the Y phylogeny within an English genealogy
The presence of Africans in Britain has been recorded since Roman times, but has left no apparent genetic trace among modern inhabitants. Y chromosomes belonging to the deepest-rooting clade of the Y… Expand
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Variation of 52 new Y-STR loci in the Y Chromosome Consortium worldwide panel of 76 diverse individuals
We have established 16 small multiplex reactions of two–four loci to amplify 52 recently described single-copy simple Y-STRs and typed these loci in a worldwide panel of 74 diverse men and two women.… Expand
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