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- Publications
- Influence
Separation of Leucas aspera, a medicinal plant of Bangladesh, guided by prostaglandin inhibitory and antioxidant activities.
- S. K. Sadhu, E. Okuyama, H. Fujimoto, M. Ishibashi
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 1 May 2003
According to the traditional usage of the plant for antiinflammation and analgesia, Leucas aspera was tested for its prostaglandin (PG) inhibitory and antioxidant activities. The extract showed both… Expand
Analgesic components of saposhnikovia root (Saposhnikovia divaricata).
- E. Okuyama, T. Hasegawa, T. Matsushita, H. Fujimoto, M. Ishibashi, M. Yamazaki
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 1 February 2001
By activity-oriented separation using the writhing method in mice, the analgesic components of Saposhnikovia root (Saposhnikovia divaricata Schischkin; Umbelliferae) were identified to be chromones,… Expand
Immunomodulatory constituents from an Ascomycete, Chaetomium seminudum.
- H. Fujimoto, M. Sumino, E. Okuyama, M. Ishibashi
- Chemistry, Medicine
- Journal of natural products
- 2004
A screening study focusing on immunomodulatory activity of the EtOAc extract of an Ascomycete, Chaetomium seminudum, has afforded a known epipolythiodioxopiperazine, chetomin (1), together with three… Expand
Immunomodulatory constituents from an ascomycete, Microascus tardifaciens.
- H. Fujimoto, T. Fujimaki, E. Okuyama, M. Yamazaki
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 15 October 1999
Fractionation guided by the immunosuppressive activity of the defatted AcOEt extract of an Ascomycete, Microascus tardifaciens, afforded eight constituents, questin (emodin 8-O-methylether) (1),… Expand
Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta.
- E. Okuyama, K. Umeyama, M. Yamazaki, Y. Kinoshita, Y. Yamamoto
- Medicine
- Planta medica
- 1 April 1995
Diffractaic acid and usnic acid were identified as the analgesic and antipyretic components of a lichen, Usnea diffracta. Both compounds showed an analgesic effect by the acetic acid-induced writhing… Expand
Pharmacologically active components of viticis fructus (Vitex rotundifolia). II. The components having analgesic effects.
- E. Okuyama, S. Fujimori, M. Yamazaki, T. Deyama
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 15 April 1998
The extract of Viticis Fructus appeared to have an analgesic effect, and was subjected to activity-guided separation using acetic acid-induced writhing in mice. The active fraction gave new… Expand
Anthraquinone production by transformed root cultures of Rubia tinctorum: Influence of phytohormones and sucrose concentration
- K. Sato, T. Yamazaki, E. Okuyama, K. Yoshihira, K. Shimomura
- Biology
- 1991
Hairy roots ofRubia tinctorum were induced by infection with Agrobacterium rhizogenes and cultured in Murashige and Skoog liquid medium containing 3% sucrose. The effects of the phytohormones IAA,… Expand
Six Immunosuppressive Features from an Ascomycete, Zopfiella longicaudata, Found in a Screening Study Monitored by Immunomodulatory Activity.
- H. Fujimoto, E. Nakamura, E. Okuyama, M. Ishibashi
- Chemistry
- 11 January 2005
Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activity.
- H. Fujimoto, E. Nakamura, E. Okuyama, M. Ishibashi
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 1 August 2004
In a screening study on immunomodulatory fungal metabolites, three known anthraquinones, carviolin (roseo-purpurin) (1), 1-O-methylemodin (2), omega-hydroxyemodin (citreorosein) (4), and a new… Expand
Analgesic principles from Aralia cordata Thunb.
- E. Okuyama, S. Nishimura, M. Yamazaki
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 25 February 1991
The analgesic principles from Aralia cordata Thunb, were identified with (ent)-kaur-16-en-19-oic acid (KA) and (ent)-pimara-8(14),15-dien-19-oic acid (PA), respectively. Both compounds were… Expand
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