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Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin- binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide
TLDR
These studies show an identical carbohydrate- specific glycolipid receptor for shigella toxin in gut and in HeLa cells and the possibility that the pilus and toxin B subunit contain homologous sequences. Expand
ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex.
TLDR
Cell adhesion by ELAM-1 is shown to be mediated by a carbohydrate ligand, sialyl-Lewis X (SLex; NeuAc alpha 2,3Gal beta 1,4(Fuc alpha 1,3)-GlcNAc-), a terminal structure found on cell-surface glycoprotein and glycolipid carbohydrate groups of neutrophils. Expand
Characterization of sialosylated Lewisx as a new tumor-associated antigen.
TLDR
Results indicate that the CSLEX1 epitope has the following structure: These results indicate that this structure had not previously been known to be tumor associated. Expand
Bacterial glycosidases for the production of universal red blood cells
TLDR
Two bacterial glycosidase gene families are reported that provide enzymes capable of efficient removal of A and B antigens at neutral pH with low consumption of recombinant enzymes. Expand
A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen SSEA-1.
TLDR
A series of glycolipid antigens reacting with the monoclonal antibody directed to the stage-specific embryonic antigen 1 was isolated and characterized from group O human erythrocyte membranes and its main feature is its long core sugar chain with a nonbranched repeating N-acetyllactosamine (norpolylactosamines). Expand
High-resolution separation and quantification of neutral lipid and phospholipid species in mammalian cells and sera by multi-one-dimensional thin-layer chromatography.
TLDR
MOD-TLC allows for direct comparative analysis of multiple samples on a single TLC plate, while still providing good resolution for the quantification of most major classes of lipid species. Expand
Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6).
TLDR
The hybridoma (FH6) secreting a monoclonal IgM antibody directed to this glycolipid was selected by reactivity of the antibody with this ganglioside and lack of reactivity with other Glycolipids having a closely related structure. Expand
A glycolipid antigen associated with Burkitt lymphoma defined by a monoclonal antibody.
TLDR
Chemical analysis of various Burkitt lymphoma cell lines revealed that the Burkittymphoma cells contained more than 100 times as much of the glycolipid antigen as was found in other human lymphoma and leukemia cell lines. Expand
Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or
TLDR
The results suggest that HMBA induces differentiation of NTERA-2 cl.D1 EC cells along a pathway distinct from the pathway(s) induced by retinoic acid and BUdR. Expand
Identification of a GH110 subfamily of alpha 1,3-galactosidases: novel enzymes for removal of the alpha 3Gal xenotransplantation antigen.
TLDR
It is determined by one-dimensional (1)H NMR spectroscopy that GH110 enzymes function with an inverting mechanism, which is in striking contrast to all other known alpha-galactosidases that use a retaining mechanism. Expand
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