Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin- binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide
- M. Jacewicz, H. Clausen, E. Nudelman, A. Donohue-Rolfe, G. Keusch
- Biology, ChemistryJournal of Experimental Medicine
- 1 June 1986
These studies show an identical carbohydrate- specific glycolipid receptor for shigella toxin in gut and in HeLa cells and the possibility that the pilus and toxin B subunit contain homologous sequences.
ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex.
- M. L. Phillips, E. Nudelman, J. Paulson
- Biology, ChemistryScience
- 23 November 1990
Cell adhesion by ELAM-1 is shown to be mediated by a carbohydrate ligand, sialyl-Lewis X (SLex; NeuAc alpha 2,3Gal beta 1,4(Fuc alpha 1,3)-GlcNAc-), a terminal structure found on cell-surface glycoprotein and glycolipid carbohydrate groups of neutrophils.
Bacterial glycosidases for the production of universal red blood cells
- Q. Liu, G. Sulzenbacher, H. Clausen
- Biology, EngineeringNature Biotechnology
- 1 April 2007
Two bacterial glycosidase gene families are reported that provide enzymes capable of efficient removal of A and B antigens at neutral pH with low consumption of recombinant enzymes.
Characterization of sialosylated Lewisx as a new tumor-associated antigen.
- K. Fukushima, M. Hirota, S. Hakomori
- BiologyCancer Research
- 1 November 1984
Results indicate that the CSLEX1 epitope has the following structure: These results indicate that this structure had not previously been known to be tumor associated.
A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen SSEA-1.
- R. Kannagi, E. Nudelman, S. Levery, S. Hakomori
- Biology, ChemistryJournal of Biological Chemistry
- 25 December 1982
High-resolution separation and quantification of neutral lipid and phospholipid species in mammalian cells and sera by multi-one-dimensional thin-layer chromatography.
- T. White, S. Bursten, D. Federighi, R. Lewis, E. Nudelman
- Biology, ChemistryAnalytical Biochemistry
- 10 April 1998
MOD-TLC allows for direct comparative analysis of multiple samples on a single TLC plate, while still providing good resolution for the quantification of most major classes of lipid species.
Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6).
- Y. Fukushi, E. Nudelman, S. Levery, S. Hakomori, H. Rauvala
- Biology, ChemistryJournal of Biological Chemistry
- 25 August 1984
A glycolipid antigen associated with Burkitt lymphoma defined by a monoclonal antibody.
- E. Nudelman, R. Kannagi, T. Tursz
- BiologyScience
- 29 April 1983
Chemical analysis of various Burkitt lymphoma cell lines revealed that the Burkittymphoma cells contained more than 100 times as much of the glycolipid antigen as was found in other human lymphoma and leukemia cell lines.
Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or…
- P. Andrews, E. Nudelman, S. Hakomori, B. Fenderson
- BiologyDifferentiation; research in biological diversity
- 1 April 1990
The results suggest that HMBA induces differentiation of NTERA-2 cl.D1 EC cells along a pathway distinct from the pathway(s) induced by retinoic acid and BUdR.
Identification of a GH110 subfamily of alpha 1,3-galactosidases: novel enzymes for removal of the alpha 3Gal xenotransplantation antigen.
- Q. Liu, H. Yuan, H. Clausen
- BiologyJournal of Biological Chemistry
- 28 March 2008
It is determined by one-dimensional (1)H NMR spectroscopy that GH110 enzymes function with an inverting mechanism, which is in striking contrast to all other known alpha-galactosidases that use a retaining mechanism.
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