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Nutraceuticals: opening the debate for a regulatory framework
Currently, nutraceuticals do not have a specific definition distinct from those of other food‐derived categories, such as food supplements, herbal products, pre‐ and probiotics, functional foods, andExpand
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Calmodulin-dependent kinase II mediates vascular smooth muscle cell proliferation and is potentiated by extracellular signal regulated kinase.
Vascular smooth muscle cell (VSMC) proliferation contributes to vascular remodeling in atherosclerosis and hypertension. Calcium-dependent signaling through calcium/calmodulin-dependent kinase IIExpand
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An N-glucosylated peptide detecting disease-specific autoantibodies, biomarkers of multiple sclerosis.
Multiple sclerosis (MS) is a complex disease that seems to depend on several pathophysiological processes. Because of its varied clinical presentation, natural history, and response to therapeuticExpand
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Online comprehensive RPLC × RPLC with mass spectrometry detection for the analysis of proteome samples.
LC-MS-based shotgun proteomics relies both on the power of the separation techniques and the sensitivity of detection methods. As a viable alternative to classical approaches in this field, weExpand
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Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors
Bovine lactoferrin is a biglobular multifunctional iron binding glycoprotein that plays an important role in innate immunity against infections. We have previously demonstrated that selected peptidesExpand
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Nutraceutical potential and antioxidant benefits of red pitaya (Hylocereus polyrhizus) extracts
Polyphenols from flesh and peels of red pitaya (Hylocereus polyrhizus) fruit were quantified by employing an extract sub-fractionation procedure applied for the first time to this fruit. HigherExpand
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Nutraceuticals: A paradigm of proactive medicine
&NA; Nutraceuticals define a new category which shades the frontier between drugs and food. As per its definition, a nutraceutical is “a food or part of a food that provides benefits health inExpand
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Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells
DNA methyltransferases (DNMTs) are important enzymes involved in epigenetic control of gene expression and represent valuable targets in cancer chemotherapy. A number of nucleoside DNMT inhibitorsExpand
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Nutraceutical potential of polyphenolic fractions from Annurca apple (M. pumila Miller cv Annurca).
The capacities of polyphenolic extracts from Annurca apple peel and flesh to inhibit the glucose and cholesterol uptake by HepG2 cells were evaluated, and compared with those of other conventionalExpand
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Nutraceutical potential of monofloral honeys produced by the Sicilian black honeybees (Apis mellifera ssp. sicula).
In the light of the growing interest in food and food products obtained through organic and environmentally friendly techniques, the present work represents the first approach to the evaluation ofExpand
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