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Identification of a New Genotype of African Swine Fever Virus in Domestic Pigs from Ethiopia
- J. Achenbach, C. Gallardo, J. Sánchez-Vizcaíno
- Biology, MedicineTransboundary and emerging diseases
- 1 October 2017
The analysis of Ethiopian ASFVs partial p72 gene sequence showed the identification of a new genotype, genotype XXIII, that shares a common ancestor with genotypes IX and X, which comprise isolates circulating in Eastern African countries and the Republic of Congo.
Novel adenovirus detected in captive bottlenose dolphins (Tursiops truncatus) suffering from self-limiting gastroenteritis
- C. Rubio-Guerri, D. García-Párraga, J. Sánchez-Vizcaíno
- Medicine, BiologyBMC Veterinary Research
- 7 March 2015
Gene sequence-based phylogenetic analysis supports a common origin of adenoviruses that affect sea mammals and suggests the need for vigilance against adenOViruses in captive and wild dolphin populations.
Distinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASP
It is proposed that cortactin binds Tir through its N-terminal part in a tyrosine and serine phosphorylation independent manner while SH3 domain binding and activation of N-WASP is regulated by tyrosines and serines mediatedosphorylation of cortactIn.
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector
It is shown that the defect relates to reduced amounts of Tir within Nck-deficient cells, which has important implications for the current model of Tir-mediated actin polymerization and opens new lines of research in this area.
First Detection of Antibodies Against African Swine Fever Virus in Faeces Samples.
- E. Nieto-Pelegrín, B. Rivera-Arroyo, J. Sánchez-Vizcaíno
- BiologyTransboundary and emerging diseases
- 1 December 2015
The findings indicate the feasibility of faecal sampling for detecting anti-ASFV antibodies, which may provide a practical non-invasive alternative for sampling wild boar populations.
Cortactin Tyrosine Phosphorylation Promotes Its Deacetylation and Inhibits Cell Spreading
It is demonstrated that cell spreading promotes the association of cortactin and FAK and that tyrosine phosphorylation of Cortactin disrupts this interaction, which may explain how it inhibits cell spreading.
Crk Adaptors Negatively Regulate Actin Polymerization in Pedestals Formed by Enteropathogenic Escherichia coli (EPEC) by Binding to Tir Effector
- E. Nieto-Pelegrín, E. Meiler, J. Martin-Villa, María Benito-León, N. Martinez-Quiles
- BiologyPLoS pathogens
- 1 March 2014
A novel role for Crk adaptors at pedestals is uncovers, opening a new perspective in how these oncoproteins regulate actin polymerization.
Porcine CLEC12B is expressed on alveolar macrophages and blood dendritic cells.
Analysis of the expression of porcine CD200R1 and CD200R1L by using newly developed monoclonal antibodies.
Characterization of the Porcine CLEC12A and Analysis of Its Expression on Blood Dendritic Cell Subsets
The porcine homolog of CLEC12A was found to be expressed on alveolar macrophages, blood conventional type 1 and type 2 DCs and plasmacytoid DCs, but not on monocytes, T cells, B cells or NK cells, in contrast to its human and murine homologicals.