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Characterization of Na+-activated K+ currents in larval lamprey spinal cord neurons.
Potassium channels play an important role in controlling neuronal firing and synaptic interactions. Na(+)-activated K(+) (K(Na)) channels have been shown to exist in neurons in different regions ofExpand
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Na+-mediated coupling between AMPA receptors and KNa channels shapes synaptic transmission
Na+-activated K+ (KNa) channels are expressed in neurons and are activated by Na+ influx through voltage-dependent channels or ionotropic receptors, yet their function remains unclear. Here we showExpand
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Differential regulation of synaptic transmission by pre- and postsynaptic SK channels in the spinal locomotor network.
The generation of activity in the central nervous system requires precise tuning of cellular properties and synaptic transmission. Neural networks in the spinal cord produce coordinated locomotorExpand
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Mechanisms of modulation of AMPA-induced Na+-activated K+ current by mGluR1.
Na(+)-activated K(+) (K(Na)) channels can be activated by Na(+) influx via ionotropic receptors and play a role in shaping synaptic transmission. In expression systems, K(Na) channels are modulatedExpand
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Endocannabinoid signaling in the spinal locomotor circuitry
To understand how the spinal central pattern generators produce locomotor movements, it is necessary to characterize the network's connectivity, the intrinsic properties of the constituent neuronsExpand
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A postsynaptic negative feedback mediated by coupling between AMPA receptors and Na+‐activated K+ channels in spinal cord neurones
Na+‐activated K+ channels (KNa) exist in different types of neurones and their activation has been shown to depend on Na+ influx via voltage‐activated channels. However, one major route for Na+Expand
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Separate signalling mechanisms underlie mGluR1 modulation of leak channels and NMDA receptors in the network underlying locomotion.
Metabotropic glutamate receptor subtype 1 (mGluR1) contributes importantly to the activity of the spinal locomotor network. For example, it potentiates NMDA current and inhibits leak conductance inExpand
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Beyond connectivity of locomotor circuitry-ionic and modulatory mechanisms.
Discrete neural networks in the central nervous system generate the repertoire of motor behavior necessary for animal survival. The final motor output of these networks is the result of theExpand
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The Role of CaV2.1 Channel Facilitation in Synaptic Facilitation
SUMMARY Activation of CaV2.1 voltage-gated calcium channels is facilitated by preceding calcium entry. Such self-modulatory facilitation is thought to contribute to synaptic facilitation. UsingExpand
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