High Genetic Diversity of Newcastle Disease Virus in Poultry in West and Central Africa: Cocirculation of Genotype XIV and Newly Defined Genotypes XVII and XVIII
A high genetic diversity, mutations in important neutralizing epitopes paired with suboptimal vaccination, various levels of clinical responses of poultry and wild birds to virulent strains, strains with new cleavage sites, and other genetic modifications found in these genotypes tend to undermine and complicate NDV management in Africa.
Evolutionary history and dynamics of dog rabies virus in western and central Africa.
A detailed analysis of the phylogeographical structure of this Africa 2 lineage revealed strong population subdivision at the country level, with only limited movement of virus among localities, including a possible east-to-west spread across Africa.
Serological surveillance of brucellosis and Q fever in cattle in the Central African Republic.
Molecular characterization of three Zika flaviviruses obtained from sylvatic mosquitoes in the Central African Republic.
Phylogenetic analysis based on the amino acid sequence of the polyprotein showed that the three ZIKV strains clustered together but diverged from all other ZikV strains, suggesting that a different subtype of West African ZIKv strains circulated in Aedes species in Central Africa.
Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus
A novel, non-discriminatory classification of monkeypox virus diversity is proposed and multiple lineages are identified within IIb, the cause of the current global outbreak, to support real-time genomic surveillance.
Identification of Ebola virus sequences present as RNA or DNA in organs of terrestrial small mammals of the Central African Republic.
Advanced Yellow Fever Virus Genome Detection in Point-of-Care Facilities and Reference Laboratories
The RT-qPCR assay is a powerful tool for reference or diagnostic laboratories with real-time PCR capability, while the isothermal RT-tHDA assay represents a useful alternative to earlier amplification techniques for the molecular diagnosis of yellow fever by field or point-of-care laboratories.
A Nosocomial Outbreak of Human Monkeypox in the Central African Republic
An outbreak of familial monkeypox occurred in the Central African Republic in 2015/2016 by 3 transmission modes: familial, health care–related, and transport-related; the viral strain responsible was a Zaire genotype strain.
Investigation of an outbreak of monkeypox in an area occupied by armed groups, Central African Republic
Temporal Patterns of Abundance of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) and Mitochondrial DNA Analysis of Ae. albopictus in the Central African Republic
- B. Kamgang, Carine Ngoagouni, A. Manirakiza, E. Nakouné, C. Paupy, M. Kazanji
- BiologyPLoS Neglected Tropical Diseases
- 1 December 2013
A comparative study early and late in the wet season in the capital and the main cities of CAR to document infestation and the ecological preferences of the two species, and Mitochondrial DNA analysis revealed broad low genetic diversity, confirming recent introduction of Ae.