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Heteroreceptor-mediated modulation of noradrenaline and acetylcholine release from peripheral nerves.
2 Heteroreceptors Modulat ing Noradrenaline Release .................................. 2.1 Muscarinic Receptors ........................................................................ 2.2 Nicotinic…
Peripheral muscarinic control of norepinephrine release in the cardiovascular system.
- E. Muscholl
- BiologyThe American journal of physiology
- 1 December 1980
Activation of muscarinic cholinergic receptors located at the terminal adrenergic nerve fiber inhibits the process of exocytotic norepinephrine (NE) release and enhances the NE release evoked by field stimulation of tissues innervated by the autonomic ground plexus.
Effect of cocaine and related drugs on the uptake of noradrenaline by heart and spleen.
- E. Muscholl
- Biology, MedicineBritish journal of pharmacology and chemotherapy
- 1 June 1961
It was concluded that cocaine specifically prevented the uptake of noradrenaline by tissues, thus increasing the amount of norADrenaline available for combination with adrenergic receptors.
A muscarinic mechanism inhibiting the release of noradrenaline from peripheral adrenergic nerve fibres by nicotinic agents.
SECRETORY RESPONSES OF EXTRAMEDULLARY CHROMAFFIN TISSUE.
- E. Muscholl, M. Vogt
- Biology, ChemistryBritish journal of pharmacology and chemotherapy
- 1 February 1964
It is suggested that the catechol amines released into the effluent fluid were derived from chromaffin tissue in the ganglion; evidence for innervation of this tissue was unobtainable, but its catechl amines were readily released by the injection of nicotinic drugs.
Muscarinic inhibition of [3H]‐noradrenaline release on rabbit iris in vitro: effects of stimulation conditions on intrinsic activity of methacholine and pilocarpine
- I. T. Bognar, S. Pallas, H. Fuder, E. Muscholl
- Biology, ChemistryBritish journal of pharmacology
- 1 July 1988
The results demonstrate a muscarinic inhibition of noradrenaline release from the rabbit isolated iris, and the activation by pilocarpine of the presynaptic receptors provides an alternative explanation for the miosis induced in the rabbit in vivo.
The determination of presynaptic pA2 values of yohimbine and phentolamine on the perfused rat heart under conditions of negligible autoinhibition
The results confirm the existence of presynaptic inhibitory α2‐adrenoceptors at the adrenergic nerve fibres of the rat heart in vitro and reveal the released endogenous transmitter apparently does not activate a negative feedback mechanism, thus permitting the determination of pA2 values.
The effect of physostigmine on the vagally induced muscarinic inhibition of noradrenaline release from the isolated perfused rabbit atria
It is concluded that the vagally induced control of noradrenaline release occurs at discrete sites rather than in a diffuse pattern at multiple terminal axon sites as is the case after exogenous muscarinic agonists.
The action of reserpine on the peripheral sympathetic system
[The concentration of noradrenalin and adrenalin in isolated sections of the heart].
- E. Muscholl
- Biology, MedicineNaunyn-Schmiedebergs Archiv fur experimentelle…
The small percentage of adrenaline indicates that the heart of these species contains only little chromaffine tissue, and the high concentration of noradrenaline in the right atrium is thought to be mainly due to the presence of adrenergic fibres.