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- Publications
- Influence
Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons
- Ricardos Tabet, E. Moutin, +14 authors H. Moine
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 27 May 2016
Significance Fragile X syndrome (FXS), the most frequent form of inherited intellectual disability, is caused by the absence of the protein Fragile X Mental Retardation Protein (FMRP) in neurons. In… Expand
Palmitoylation of cdc42 Promotes Spine Stabilization and Rescues Spine Density Deficit in a Mouse Model of 22q11.2 Deletion Syndrome
- E. Moutin, I. Nikonenko, +4 authors D. Muller
- Biology, Medicine
- Cerebral cortex
- 29 June 2016
22q11.2 deletion syndrome (22q11DS) is associated with learning and cognitive dysfunctions and a high risk of developing schizophrenia. It has become increasingly clear that dendritic spine… Expand
Rho-GTPase-activating Protein Interacting with Cdc-42-interacting Protein 4 Homolog 2 (Rich2)
- F. Raynaud, E. Moutin, +5 authors L. Fagni
- Biology, Medicine
- The Journal of Biological Chemistry
- 18 December 2013
Background: Rich2 is a synaptic Rho-GAP (Rho-GTPase-activating protein) the target of which was unknown. Results: We found that Rich2 controls dendritic spine morphogenesis by inhibiting Rac1… Expand
Procedures for Culturing and Genetically Manipulating Murine Hippocampal Postnatal Neurons
- E. Moutin, Anne-Laure Hemonnot, +4 authors V. Compan
- Biology, Medicine
- Frontiers in Synaptic Neuroscience
- 30 April 2020
Neuronal hippocampal cultures are simple and valuable models for studying neuronal function. While embryonic cultures are widely used for different applications, mouse postnatal cultures are still… Expand
PNAS Plus Significance Statements
- Rachel M Barry, L. Hidde, +9 authors J. Merrer
- Medicine
- Proceedings of the National Academy of Sciences
- 14 June 2016
Many immune responses are mediated by direct cell–cell interactions and develop over multiple timescales. A mechanistic understanding of how diverse outcomes arise during these interactions entails… Expand