• Publications
  • Influence
Selegiline and desmethylselegiline stimulate NGF, BDNF, and GDNF synthesis in cultured mouse astrocytes.
We investigated the effects of selegiline and desmethylselegiline on synthesis of neurotrophic factors in cultured mouse astrocytes. Treatment with 2 mM selegiline for 24 h increased the contents ofExpand
Tumor necrosis factor gene polymorphisms in patients with sporadic Parkinson's disease
We studied promoter region polymorphisms in the tumor necrosis factor (TNF) gene at position -1031, -863, and -857, in 172 Japanese patients with sporadic Parkinson's disease (PD). The frequency ofExpand
Influence of interleukin-1β gene polymorphisms on age-at-onset of sporadic Parkinson's disease
We studied genetic polymorphisms in the promoter region (position -511) and exon 5 (position +3953) of the interleukin (IL)-1β gene in 122 Japanese patients with Parkinson's disease (PD) and 112Expand
A collaborative study on the malignant syndrome in Parkinson's disease and related disorders.
We report the results of a collaborative study on malignant syndrome (MS) that developed in patients being treated with levodopa and other anti-parkinsonian drugs. We analyzed clinical features,Expand
Diagnostic accuracy of cardiac metaiodobenzylguanidine scintigraphy in Parkinson disease
Background and purpose:  To estimate the diagnostic accuracy of cardiac 123I‐metaiodobenzylguanidine (MIBG) scintigram for detection of Parkinson disease.
"Quality of life" assessment of urination in elderly Japanese men and women with some medical problems using International Prostate Symptom Score and King's Health Questionnaire.
OBJECTIVES To investigate the relationships among lower urinary tract symptoms (LUTS), satisfaction at urination, and quality of life (QoL) in elderly Japanese men and women, who attended physiciansExpand
Therapeutic effects of dopamine D1/D2 receptor agonists on detrusor hyperreflexia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned parkinsonian cynomolgus monkeys.
The effects of dopamine receptor agonists on urinary bladder function were evaluated in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned parkinsonian cynomolgus monkeys toExpand
Apomorphine up-regulates NGF and GDNF synthesis in cultured mouse astrocytes.
Apomorphine, a D1/D2 dopamine agonist, is an anti-parkinsonian drug. We examined the effects of apomorphine on synthesis of neurotrophic factors in cultured mouse astrocytes. After 24 h incubationExpand
Influence of interleukin-1beta gene polymorphisms on age-at-onset of sporadic Parkinson's disease.
We studied genetic polymorphisms in the promoter region (position -511) and exon 5 (position +3953) of the interleukin (IL)-1beta gene in 122 Japanese patients with Parkinson's disease (PD) and 112Expand
Meta-analysis of α synuclein/ NACP polymorphism in Parkinson's disease in Japan
α Synuclein is a presynaptic protein highly and broadly expressed in the brain but its normal function is unknown.1 The protein is also termed non-amyloid β component precursor (NACP) because of itsExpand
...
1
2
3
4
5
...