• Publications
  • Influence
Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study
TLDR
Around one child in every three was infected with 2009 pandemic H1N1 in the first wave of infection in regions with a high incidence, ten times more than estimated from clinical surveillance. Expand
Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study.
TLDR
Despite much serotype replacement, a substantial reduction in invasive pneumococcal disease in young children can be achieved with PCV7 vaccination, with some indirect benefit in older age groups. Expand
Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction
TLDR
For children vaccinated in the routine infant immunisation programme, the effectiveness of the MCC vaccine fell to low levels after only 1 year, and alternative routine immunisation schedules should be considered to ensure high levels of protection are sustained. Expand
Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study.
TLDR
The herd protection induced byPCV7 is continuing, and similar indirect protection is occurring from the additional serotypes covered by PCV13, but there is, however, evidence of increasing invasive pneumococcal disease due to non-PCV13 serotypes, particularly in children younger than 5 years in 2014. Expand
Population‐based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40
TLDR
There is no serological evidence that SV40 entered the human population during the past 80 years, and the possibility of cross‐reaction with BKV or JCV antibody must be considered. Expand
Consequences of varicella and herpes zoster in pregnancy: prospective study of 1739 cases
TLDR
In a joint prospective study in Germany and the United Kingdom between 1980 and 1993, 1373 women who had varicella and 366 who had herpes zoster during the first 36 weeks of gestation were followed up, providing a sound basis for counselling women withvaricella in pregnancy. Expand
Serotype-specific effectiveness and correlates of protection for the 13-valent pneumococcal conjugate vaccine: a postlicensure indirect cohort study.
TLDR
The vaccine effectiveness for PCV13 and PCV7 was lower than predicted by the aggregate correlate of protection of 0·35 μg/mL used during licensing, and serotype-specific correlates of protection vary widely. Expand
The comparative sero-epidemiology of varicella zoster virus in 11 countries in the European region.
TLDR
Most VZV infection occurred in childhood, but there was a wide variation in transmissibility, with R(0) ranging from 16.9 in the Netherlands to 3.3 in Italy, and herd immunity thresholds varied from 70% in Italy to 94% in the Dutch. Expand
Impact of anti-vaccine movements on pertussis control: the untold story
TLDR
Pertussis incidence was 10 to 100 times lower in countries where high vaccine coverage was maintained than in countriesWhere immunisation programs were compromised by anti-vaccine movements, showing that these vaccines continue to have an important role in global immunisation. Expand
Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: population study
TLDR
Findings provide no support for an MMR associated “new variant” form of autism with developmental regression and bowel problems, and further evidence against involvement of MMR vaccine in the initiation of autism. Expand
...
1
2
3
4
5
...