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Tissue ascorbic acid analysis using ferrozine compared with the dinitrophenylhydrazine method.
Guinea pig tissues and human plasma and serum samples were used to compare this ferrozine method with the dinitrophenylhydrazine assay which measures (total) ascorbic acid by a different chemical principle.
The relationship of the urinary ascorbate metabolites to specific levels of ascorbate supplementation in the monkey.
The distribution of 14C in the four peaks was dependent upon the ascorbate nutritional status of the monkey and remained constant for at least 30 days postlabel, and the two major fractions were identified as oxalate and unmetabolized ascorBate.
Erythrocyte filterability, fragility, and membrane proteins in folic acid deficient guinea pigs.
Folate deficiency in guinea pigs did cause guinea pig erythrocytes to be markedly less susceptible to hypotonic lysis than cells from control animals, a feature which is not characteristic of human megaloblastic anemia.
Results with commercial radioassay kits compared with microbiological assay of folate in serum and whole-blood.
Radioassay kits appear to be suitable diagnostic agents for serum folate, if the behavior of a particular kit is investigated thoroughly before its routine use, but the diagnostic value of radioassays of erythrocyte folate needs to be validated.
Histologic Changes in Nude Mouse Skin and Human Skin Xenografts Following Exposure to Sulfhydryl Reagents: Arsenicals
Nude mouse skin reacted faster to PDA than did the grafts, but the histological changes were similar, and nude mouse hair follicles and sebaceous glands showed similar cellular changes at approximately the same time as did epidermal cells.
A continuous-flow (AutoAnalyzer II) procedure for measuring erythrocyte transketolase activity.
In this semiautomated method, an AutoAnalyzer II is used to measure the enzymic production of glyceraldehyde 3-phosphate in hemolysates, to assay erythrocyte transketolase (EC activity.
Thiosulfate as an Antidote to Mustard Poisoning, A Review of the Literature.
Abstract : This report reviews the multidisciplinary literature (from World War I to the present) on sodium thiosulfate as an antidote to sulfur and nitrogen mustards. Intramolecular cyclization of
Reduction of extracellular methemoglobin by erythrocytes.
Observations indicate that the transfer of reducing equivalents across the erythrocyte membrane and reduction of extracellular methemoglobin can be accomplished by release and recycling of ascorbic acid.
One-dimensional and two-dimensional nuclear magnetic resonance studies of the reaction of phenyldichloroarsine with glutathione.
One-dimensional and two-dimensional nuclear magnetic resonance spectroscopy were used to confirm the structure of the adduct and elucidate its stereochemistry, stability, and reactivity.