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Exercise training increases size of hippocampus and improves memory
The hippocampus shrinks in late adulthood, leading to impaired memory and increased risk for dementia. Hippocampal and medial temporal lobe volumes are larger in higher-fit adults, and physicalExpand
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Cardiovascular fitness, cortical plasticity, and aging.
Cardiovascular fitness is thought to offset declines in cognitive performance, but little is known about the cortical mechanisms that underlie these changes in humans. Research using animal modelsExpand
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Aerobic exercise training increases brain volume in aging humans.
BACKGROUND The present study examined whether aerobic fitness training of older humans can increase brain volume in regions associated with age-related decline in both brain structure and cognition.Expand
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The physical activity scale for the elderly (PASE): evidence for validity.
We assessed the validity of the Physical Activity Scale for the Elderly (PASE) in a sample of sedentary adults (56 men, 134 women, mean age +/- [SD] 66.5+/-5.3 years) who volunteered to participateExpand
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Aerobic fitness reduces brain tissue loss in aging humans.
BACKGROUND The human brain gradually loses tissue from the third decade of life onward, with concomitant declines in cognitive performance. Given the projected rapid growth in aged populations, andExpand
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Ageing, fitness and neurocognitive function
In the ageing process, neural areas, and cognitive processes, do not degrade uniformly. Executive control processes and the prefrontal and frontal brain regions that support them show large andExpand
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The physical activity scale for individuals with physical disabilities: development and evaluation.
OBJECTIVE To evaluate the construct validity of a new 13-item physical activity survey designed to assess physical activity in individuals with physical disabilities. DESIGN Mail survey requestingExpand
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Tai Chi and fall reductions in older adults: a randomized controlled trial.
BACKGROUND The authors' objective was to evaluate the efficacy of a 6-month Tai Chi intervention for decreasing the number of falls and the risk for falling in older persons. METHODS ThisExpand
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Aerobic fitness is associated with hippocampal volume in elderly humans
Deterioration of the hippocampus occurs in elderly individuals with and without dementia, yet individual variation exists in the degree and rate of hippocampal decay. Determining the factors thatExpand
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Plasticity of Brain Networks in a Randomized Intervention Trial of Exercise Training in Older Adults
Research has shown the human brain is organized into separable functional networks during rest and varied states of cognition, and that aging is associated with specific network dysfunctions. TheExpand
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