• Publications
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Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL).
Criteria for the immunological classification of acute leukemias are proposed by a recently established European group designated EGIL. The main aims of EGIL are to establish guidelines for theExpand
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The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL.
We have investigated the role of immunophenotyping in distinguishing between leukemic B-cell lymphoproliferative disorders. Circulating cells from 666 cases were analyzed with a panel of markers byExpand
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A subset of t(11;14) lymphoma with mantle cell features displays mutated IgVH genes and includes patients with good prognosis, nonnodal disease.
We analyzed lymphocyte morphology, histology, immunophenotype, immunoglobulin heavy chain (IgVH) gene mutations, and clinical course in 80 unselected patients presenting with circulating t(11;14)Expand
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Outcome of biphenotypic acute leukemia.
BACKGROUND AND OBJECTIVE Although biphenotypic leukemia is now a defined entity, outcome of this rare form of acute leukemia has not been well documented. We present the first comprehensive studyExpand
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Improvement of the chronic lymphocytic leukemia scoring system with the monoclonal antibody SN8 (CD79b).
  • E J Moreau, E. Matutes, +5 authors D. Catovsky
  • Medicine
  • American journal of clinical pathology
  • 1 October 1997
A scoring system, based on the immunophenotypic analysis of a panel of five membrane markers (CD5, CD22, CD23, FMC7, SmIg) was shown to be useful in the distinction between chronic lymphocyticExpand
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Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial
BACKGROUND Previous studies of patients with chronic lymphocytic leukaemia reported high response rates to fludarabine combined with cyclophosphamide. We aimed to establish whether this treatmentExpand
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Levels of expression of CD19 and CD20 in chronic B cell leukaemias.
AIMS: To investigate whether the antigen levels of the B cell lineage markers CD19 and CD20 can distinguish between normal and neoplastic B cells or characterise distinct expression patterns amongExpand
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Definition of acute biphenotypic leukemia.
BACKGROUND AND OBJECTIVE A minority of acute leukemias have features characteristic of both the myeloid and lymphoid lineages and for this reason are designated mixed-lineage, hybrid or biphenotypicExpand
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A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia
We conducted a genome-wide association study of 299,983 tagging SNPs for chronic lymphocytic leukemia (CLL) and performed validation in two additional series totaling 1,529 cases and 3,115 controls.Expand
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High remission rate in T-cell prolymphocytic leukemia with CAMPATH-1H.
T-cell prolymphocytic leukemia (T-PLL) is a chemotherapy-resistant malignancy with a median survival of 7.5 months. Preliminary results indicated a high remission induction rate with the human CD52Expand
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