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Pax6 defines the di-mesencephalic boundary by repressing En1 and Pax2.
TLDR
The results of misexpression experiments, together with normal expression patterns of Pax6, En1 and Pax2, suggest that repressive interaction between Pax6 and En1/Pax2 defines the di-mesencephalic boundary. Expand
RGM and its receptor neogenin regulate neuronal survival
TLDR
To understand the functions of RGM–neogenin complexes in vivo, gene transfer technology was used to perturb their expression in the developing neural tube of chick embryos and found neogenin over-expression or RGM down-expression in the neural tube induces apoptosis. Expand
The Slit Receptor Rig-1/Robo3 Controls Midline Crossing by Hindbrain Precerebellar Neurons and Axons
TLDR
It is demonstrated that Rig-1 controls the ability of both precerebellar neuron cell bodies and their axons to cross the midline, as well as neurons of the lateral reticular nucleus and basilar pons. Expand
Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development.
TLDR
The relationship among isthmus related genes is examined, the mechanism of the formation and maintenance of isthmic organizing activity is discussed, and the role of Wnt1 is considered. Expand
Role of Pax3/7 in the tectum regionalization.
TLDR
Results of misexpression experiments suggest that Pax3 and Pax7 define the tectum region subsequent to the function of Otx2 and En, which is well consistent with presumptive tectorum region in a dorsoventral axis. Expand
Repulsive Guidance Molecule Plays Multiple Roles in Neuronal Differentiation and Axon Guidance
TLDR
This work provides the first evidence for a role for RGMs in axon guidance in vivo and suggests that RGMa exerts multiple functions during neural development. Expand
Isthmus organizer for midbrain and hindbrain development
TLDR
A strong Fgf8 signal activates the Ras-ERK signaling pathway, which in turn activates Irx2 in a rostrodorsal part of the hindbrain, and forces this tissue to differentiate into cerebellum. Expand
Repulsive guidance molecule/neogenin: a novel ligand‐receptor system playing multiple roles in neural development
TLDR
RGM/neogenin is a novel dependence ligand/receptor couple as well as an axon guidance molecular complex, suggesting that they do not only control the guidance of visual axons. Expand
Differential Cadherin Expression in the Developing Postnatal Telencephalon of a New World Monkey
TLDR
In contrast to rodents, cadherin expression was reduced overall and localized to restricted areas of the brain during the developmental process, suggesting that cadherins are more crucially involved in developmental or maturation processes rather than in neural functioning. Expand
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