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Patterns of care and outcome for patients with glioblastoma diagnosed during 2008-2010 in Spain.
BACKGROUND To assess management patterns and outcome in patients with glioblastoma multiforme (GBM) treated during 2008-2010 in Spain. METHODS Retrospective analysis of clinical, therapeutic, andExpand
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CSF1R Protein Expression in Reactive Lymphoid Tissues and Lymphoma: Its Relevance in Classical Hodgkin Lymphoma
Tumour-associated macrophages (TAMs) have been associated with survival in classic Hodgkin lymphoma (cHL) and other lymphoma types. The maturation and differentiation of tissue macrophages dependsExpand
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SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018)
Febrile neutropenia (FN) is a common dose-limiting toxicity of chemotherapy, with a profound impact on the evolution of patients with cancer, due to the potential development of seriousExpand
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Local recurrence after five years is associated with preoperative chemoradiotherapy treatment in patients diagnosed with stage II and III rectal cancer.
AIM To asses the moment of local recurrence and its influence on the appraisal of the results of neoadjuvant chemoradiotherapy (CRT). METHODS We evaluated 317 patients with a preoperative diagnosisExpand
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Complications from the primary tumour are not related with survival in patients with synchronous stage IV colorectal cancer receiving chemotherapy without primary tumour resection
BackgroundThe aim of this study was to evaluate the rate of complications from the primary tumour (CPT) requiring surgical or endoscopic intervention during chemotherapy treatment in patients withExpand
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Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets
Defining the mutational landscape of classic Hodgkin lymphoma is still a major research goal. New targeted next-generation sequencing (NGS) techniques may identify pathogenic mechanisms and newExpand
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Circulating Tumor Cells in Patients Undergoing Resection of Colorectal Cancer Liver Metastases. Clinical Utility for Long-Term Outcome: A Prospective Trial
BackgroundPatients with resected colorectal cancer liver metastases display heterogeneous clinical behavior. The identification of new prognostic factors would help in making more accurateExpand
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Crizotinib in advanced ALK-positive non-small cell lung cancer: Results of a retrospective cohort in Complejo Hospitalario de Navarra, Spain.
e19158 Background: Crizotinib is an oral tyrosine kinase inhibitor that targets anaplastic lymphoma kinase (ALK) and has been approved in several countries for treatment of advanced ALK-positive no...
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Genomic analyses of microdissected Hodgkin and Reed-Sternberg cells: mutations in epigenetic regulators and p53 are frequent in refractory classic Hodgkin lymphoma
This work was supported by grants from the Plan Nacional de I + D + I cofinanced by the ISCIII-Subdireccion General de Evaluacion and the Fondo Europeo de Desarrollo Regional (FEDER), PI12/1832,Expand
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Is aflibercept an optimal treatment for wt RAS mCRC patients after progression to first line containing anti-EGFR?
To determine the efficacy and safety data of aflibercept + FOLFIRI in wt RAS mCRC patients after progression to standard chemotherapy + anti-EGFR treatment. Retrospective, observational study in realExpand
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