• Publications
  • Influence
Vasoactive effect of endothelin‐1 on rat liver in vivo
TLDR
Endothelin‐1 decreased hepatic tissue oxygenation associated with sinusoidal vasoconstriction at high concentrations of endothelin-1, which results in hepatocellular damage. Expand
Clarithromycin Versus Metronidazole as First-line Helicobacter pylori Eradication: A Multicenter, Prospective, Randomized Controlled Study in Japan
TLDR
Metronidazole-based therapy (RAM) was superior to standard CLR- based therapy (RAC) for first-line H. pylori eradication, reflecting the progressive increase in CLR resistance observed in Japan. Expand
Endothelin‐1 is involved in the pathogenesis of ischemia/reperfusion liver injury by hepatic microcirculatory disturbances
TLDR
Endothelin‐1 appears to be involved in the microcirculatory disturbance and histological damage in the liver after ischemia/reperfusion. Expand
Roles of endothelin-1 and nitric oxide in the mechanism for ethanol-induced vasoconstriction in rat liver.
TLDR
The hypothesis that two endothelium-derived vasoactive factors, endothelin-1 and nitric oxide, regulate hepatic vascular tone in the presence of ethanol is supported. Expand
RGM1, a cell line derived from normal gastric mucosa of rat
TLDR
Character and usefulness of RGM1 cells are examined, indicating that RGM 1 cells are epithelial in origin and like gastric mucous epithelial cells or mucous neck cells, and many granules are visible in the cytoplasm. Expand
Role of endogenous endothelin in pathogenesis of ethanol-induced gastric mucosal injury in rats.
TLDR
The major objective of this study was to elucidate the role of endogenous endothelin (ET)-1, a potent vasoconstrictor peptide, in the pathogenesis of ethanol (EtOH)-induced gastric mucosal injury and to examine whether pretreatment with anti-ET-1 antibody protected against EtOH-induced mucosal Injury by improving mucosal microcirculation. Expand
Randomized comparative study of omeprazole and famotidine in reflux esophagitis
TLDR
The effects of omeprazole (OMP) and famotidine (FAM) on RE have been examined in a randomized comparative study. Expand
Ethanol stimulates immunoreactive endothelin-1 and -2 release from cultured human umbilical vein endothelial cells.
TLDR
Ethanol was found to directly stimulate ET1 + 2 release from cultured human umbilical vein endothelial cells, which may be related to ethanol-induced cardiovascular diseases such as hypertension, myocardial infarction and stroke, as well as fatal alcohol syndrome. Expand
Role of endothelin 1 in hemorrhagic shock-induced gastric mucosal injury in rats.
TLDR
The results suggest that endogenous ET-1 plays an important role in the pathogenesis of hemorrhage shock-induced gastric mucosal damage through impairment of mucosal microcirculation. Expand
Endogenous nitric oxide attenuates ethanol‐induced perturbation of hepatic circulation in the isolated perfused rat liver
TLDR
It is suggested that endogenous nitric oxide acts as a vasodilator that reduces ethanol‐induced vasoconstriction, thus improving microcirculation and leading to decreased hepatic damage. Expand
...
1
2
3
4
5
...