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Interactions between location and task affect the spatial and directional firing of hippocampal neurons
TLDR
When rats forage for randomly dispersed food in a high walled cylinder the firing of their hippocampal “place” cells exhibits little dependence on the direction faced by the rat. Expand
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Sex differences and correlations in a virtual Morris water task, a virtual radial arm maze, and mental rotation
Different tasks are often used to assess spatial memory in humans compared to nonhumans. In order to bridge this paradigmatic gap, we used a within-subject design to test 61 undergraduates on threeExpand
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Spatial information content and reliability of hippocampal CA1 neurons: Effects of visual input
The effects of darkness on quantitative spatial firing characteristics of 235 hippocampal CA1 “complex spike” (CS) cells were studied in young and old Fischer‐344 rats during food‐motivatedExpand
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Sex differences and estrous cycle changes in hippocampus-dependent fear conditioning
Male and naturally cycling female rats were tested in a fear conditioning paradigm that encompassed both hippocampus-dependent and -independent components. The females were both conditioned andExpand
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Age‐related deficits on the radial maze and in fear conditioning: Hippocampal processing and consolidation
Young adult, middle‐aged, and old male F‐344 rats were assessed for their hippocampal ability. This was accomplished by examining the animals on two different paradigms, each incorporating aExpand
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Disambiguating the similar: The dentate gyrus and pattern separation
The human hippocampus supports the formation of episodic memory without confusing new memories with old ones. To accomplish this, the brain must disambiguate memories (i.e., accentuate theExpand
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Neocortical synaptogenesis, aging, and behavior: Lifespan development in the motor-sensory system of the rat
Little evidence presently exists on the development and aging of synaptic contacts and their relationship to behavior, particularly in nonvisual brain areas. To investigate this interrelationship,Expand
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Dissociation between Dorsal and Ventral Hippocampal Theta Oscillations during Decision-Making
Hippocampal theta oscillations are postulated to support mnemonic processes in humans and rodents. Theta oscillations facilitate encoding and spatial navigation, but to date, it has been difficult toExpand
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Conflict between place and response navigation strategies: effects on vicarious trial and error (VTE) behaviors.
Navigation can be accomplished through multiple decision-making strategies, using different information-processing computations. A well-studied dichotomy in these decision-making strategies comparesExpand
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Scopolamine induced deficits in a battery of rat cognitive tests: comparisons of sensitivity and specificity
Despite much research, the cognitive effects of scopolamine hydrobromide, a cholinergic antagonist, remain controversial. Scopolamine affects multiple systems each of which can impact behavior. OneExpand
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