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Transdermal delivery of ketorolac tromethamine: permeation enhancement, device design, and pharmacokinetics in healthy humans.
Transdermal delivery of ketorolac tromethamine, a potent non-narcotic analgesic, through human skin in vitro and in vivo was investigated. In order to enhance and sustain the flux of ketorolac… Expand
Permeability of ketorolac acid and its ester analogs (prodrug) through human cadaver skin.
The in vitro skin permeabilities of ketorolac acid (KA), a potent nonsteroidal analgesic, and its two ester analogs as prodrug through human cadaver skin were investigated. The two esters of KA,… Expand
Micellar Solubilization of Timobesone Acetate in Aqueous and Aqueous Propylene Glycol Solutions of Nonionic Surfactants
The micellar solubilization of timobesone acetate, a novel topical corticosteroid, was studied in aqueous and aqueous propylene glycol solutions of 1 to 5% nonionic surfactants at 25°C. The… Expand
Absorption of transdermally delivered ketorolac acid in humans.
Transdermal delivery of ketorolac acid, a potent analgesic, through human skin in vitro and in vivo was evaluated. The following three transdermal solutions were selected to study the in vitro skin… Expand
Glycolysis in dog skeletal muscle.
Permeability of pure enantiomers of ketorolac through human cadaver skin.
- S. D. Roy, D. Chatterjee, E. Manoukian, A. Divor
- Chemistry, Medicine
- Journal of pharmaceutical sciences
- 1 August 1995
The permeability of pure enantiomers of ketorolac acid, a potent non-narcotic analgesic, through human cadaver skin was evaluated. The melting temperature of each enantiomer was 20 degrees C higher… Expand
Steady‐State Level of Phosphocreatine in the Heart
The enzymatic microestimation of inosine, adenosine and inosinic acid.
Release of Lonapalene from Two-Phase Emulsion-Type Ointment Systems
The in vitro release of lonapalene, a novel nonsteroidal antipsoriatic agent, was studied from two-phase emulsion-type ointment systems into a perfect sink of propylene carbonate at 32°C. Lonapalene… Expand
The Enzymatic Microestimation of Urea
Since the reaction goes to completion under experimental conditions, the decrease in extinction (ZlE) at 340 nm is a measure of the amount of NAD formed and thus of the quantity of ammonia present.… Expand