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Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.
TLDR
It is shown that endothelial cells have the potential to metabolically modify the LDL molecule, generating a form that is more rapidly degraded by macrophages and that is recognized by the macrophage receptor for acetylated LDL. Expand
Relative lipophilicities, solubilities, and structure-pharmacological considerations of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors pravastatin, lovastatin, mevastatin, and
The apparent octanol-water partition coefficients (Po/w) and aqueous solubilities for four 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors [pravastatin, lovastatin (mevinolin),Expand
Nonenzymatic Glucosylation of Low-Density Lipoprotein Alters Its Biologic Activity
TLDR
Since, like other plasma proteins, LDL undergoes glucosylation in diabetes, its turnover and sites of catabolism may differ from normal and this may be relevant to the accelerated atherosclerosis of diabetes. Expand
Declining immune function in children and adolescents with hemophilia and HIV infection: effects on neuropsychological performance. Hemophilia Growth and Development Study.
TLDR
Declines in neuropsychological functioning are directly related to declines in immune functioning in HIV+ children, adolescents, and young adults with hemophilia. Expand
Enhanced Macrophage Degradation of Biologically Modified Low Density Lipoprotein
TLDR
A biologically generated modification of LDL is described that markedly alters cholesterol metabolism of macrophages and, consequently, may play a role in foam cell formation during atherogenesis. Expand
The effect of calcium on microbial aggregation during uasb reactor start up
The dynamics of granule formation were studied using cells from two bench-scale UASB Reactors. The objective was to elucidate factors which influence formation and maintenance of highly activeExpand
HIV-associated changes in adaptive, emotional, and behavioral functioning in children and adolescents with hemophilia: results from the Hemophilia Growth and Development Study.
TLDR
According to their caregivers, boys with hemophilia and HIV infection showed considerable resilience with regard to adaptive behavior and emotional and behavioral problems, however, over time changes occurred in these areas that appear to be related to immune functioning. Expand
ORIGIN, GENETIC DIVERSITY, AND POPULATION STRUCTURE OF NECTRIA COCCINEA VAR. FAGINATA IN NORTH AMERICA
Genetic similarity of Nectria coccinea var. faginata (NCF) from the northeastern USA to other Nectria taxa was investigated using RFLPs of ribosom- al (r) DNA, mitochondrial (mt) DNA, and anony-
Lipoprotein lipase secretion by human monocytes and rabbit alveolar macrophages in culture.
TLDR
The expression of lipoprotein lipase secretion by human monocytes may have important implications with respect to the development of foam cells in the arterial wall during atherogenesis. Expand
INTERACTIONS OF PLASMA LIPOPROTEINS WITH ENDOTHELIAL CELLS *
TLDR
Interaction of plasma lipoproteins with endothelial cells is generally considered to be of fundamental importance in the pathogenesis of atherosclerosis and the effects of lipoprotein-endothelial cell interaction can be considered in two reciprocal categories. Expand
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