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HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer
BackgroundColorectal cancer (CRC) is a common cancer worldwide. The main cause of death in CRC includes tumor progression and metastasis. At molecular level, these processes may be triggered byExpand
Exome analysis of carotid body tumor
BackgroundCarotid body tumor (CBT) is a form of head and neck paragangliomas (HNPGLs) arising at the bifurcation of carotid arteries. Paragangliomas are commonly associated with germline and somaticExpand
Transcriptome analysis reveals mechanisms of geroprotective effects of fucoxanthin in Drosophila
BackgroundWe have previously showed that the carotenoid fucoxanthin can increase the lifespan in Drosophila melanogaster and Caenorhabditis elegans. However, the molecular mechanisms of theExpand
Grain refinement, texture, and mechanical properties of a magnesium alloy after radial-shear rolling
Abstract Microstructure (including its uniformity), texture, and mechanical properties of Mg-Al-Zn-Mn alloy billets after radial-shear rolling (RSR) were investigated. RSR with the temperature in theExpand
Bioinformatic identification of differentially expressed genes associated with prognosis of locally advanced lymph node-positive prostate cancer
Prostate cancer (PCa) is one of the primary causes of cancer-related mortality in men worldwide. Expand
Features of in vitro and in vivo behaviour of magnesium alloy WE43
Abstract Biocompatibility of magnesium alloy WE43 was investigated under in vitro and in vivo conditions. The biodegradation of WE43 samples in vitro was found to occur very rapidly. The evolution ofExpand
Differentially Expressed Genes Associated With Prognosis in Locally Advanced Lymph Node-Negative Prostate Cancer
Older age is one of the main risk factors for cancer development. The incidence of prostate cancer, as a multifactorial disease, also depends upon demographic factors, race, and geneticExpand
Mutational load in carotid body tumor
BackgroundCarotid body tumor (CBT) is a rare neoplasm arising from paraganglion located near the bifurcation of the carotid artery. There is great intra-tumor heterogeneity, and CBT development couldExpand
The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma
BackgroundCpG island methylator phenotype (CIMP) is found in 15–20% of malignant colorectal tumors and is characterized by strong CpG hypermethylation over the genome. The molecular mechanisms ofExpand
[Novel Genes Associated with the Development of Carotid Paragangliomas].
Carotid paragangliomas (CPGLs) are rare neuroendocrine tumors of the head and neck. "Germline" and somatic mutations in a number of genes were shown to be associated with the development of CPGLs;Expand