E. Leitner

Publications242
h-index28
Citations2,671
Highly Influential Citations128
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Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae.
In the yeast Saccharomyces cerevisiae, two acyl-CoA:sterol acyltransferases (ASATs) that catalyze the synthesis of steryl esters have been identified, namely Are2p (Sat1p) and Are1p (Sat2p). Deletion… Expand
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Structural and Biochemical Properties of Lipid Particles from the Yeast Saccharomyces cerevisiae*
The two most prominent neutral lipids of the yeast Saccharomyces cerevisiae, triacylglycerols (TAG) and steryl esters (SE), are synthesized by the two TAG synthases Dga1p and Lro1p and the two SE… Expand
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Determination of the nicotine content of various edible nightshades (Solanaceae) and their products and estimation of the associated dietary nicotine intake.
This investigation was initiated as a result of proposals in the literature that dietary nicotine intake could contribute to the level of nicotine metabolites in biological fluids such as salivary… Expand
  • 105
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Penicillium chrysogenum extracellular acid phosphatase: purification and biochemical characterization.
An extracellular acid phosphatase (EC 3.1.3.2) from crude culture filtrate of Penicillium chrysogenum was purified to homogeneity using high-performance ion-exchange chromatography and size-exclusion… Expand
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The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame
Cyclosporin A, a potent and clinically-important immunosuppressive drug (SandimmunR), is synthesized from its precursor amino acids by cyclosporin synthetase, a single multi-functional enzyme. In… Expand
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Oleate Inhibits Steryl Ester Synthesis and Causes Liposensitivity in Yeast*
In the yeast Saccharomyces cerevisiae, neutral lipids can be synthesized by four acyltransferases, namely Dga1p and Lro1p producing triacylglycerols (TAG) and Are1p and Are2p forming steryl esters… Expand
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Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris.
The sesquiterpenoid (+)-nootkatone is a highly demanded and highly valued aroma compound naturally found in grapefruit, pummelo or Nootka cypress tree. Extraction of (+)-nootkatone from plant… Expand
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Quorum-sensing effects in the antagonistic rhizosphere bacterium Serratia plymuthica HRO-C48.
The rhizosphere-associated bacterium Serratia plymuthica HRO-C48 is not only able to suppress symptoms caused by soil-borne pathogens but is also able to stimulate growth of plants. Detailed… Expand
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A specific structural requirement for ergosterol in long-chain fatty acid synthesis mutants important for maintaining raft domains in yeast.
Fungal sphingolipids contain ceramide with a very-long-chain fatty acid (C26). To investigate the physiological significance of the C26-substitution on this lipid, we performed a screen for mutants… Expand
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Lipid composition of peroxisomes from the yeast Pichia pastoris grown on different carbon sources.
Highly purified peroxisomes from the yeast Pichia pastoris grown on methanol or oleic acid, respectively, were used to characterize the lipid composition of this organelle. For this purpose, an… Expand
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