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Impact of Circadian Nuclear Receptor REV-ERBα on Midbrain Dopamine Production and Mood Regulation
The circadian nature of mood and its dysfunction in affective disorders is well recognized, but the underlying molecular mechanisms are still unclear. Here, we show that the circadian nuclearExpand
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Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase
For the synthesis of polylactic acid (PLA) and its copolymers by one‐step fermentation process, heterologous pathways involving Clostridium propionicum propionate CoA transferase (PctCp) andExpand
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Toxicity of 100 nm zinc oxide nanoparticles: a report of 90-day repeated oral administration in Sprague Dawley rats
Nanoparticles (NPs) are used commercially in health and fitness fields, but information about the toxicity and mechanisms underlying the toxic effects of NPs is still very limited. The aim of thisExpand
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Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis.
Lipid rafts, plasma membrane microdomains, are important for cell survival signaling and cholesterol is a critical lipid component for lipid raft integrity and function. DHA is known to have poorExpand
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Diagnostic Efficacy of PET/CT Plus Brain MR Imaging for Detection of Extrathoracic Metastases in Patients with Lung Adenocarcinoma
We aimed to evaluate prospectively the efficacy of positron emission tomography (PET)/computed tomography (CT) plus brain magnetic resonance imaging (MRI) for detecting extrathoracic metastases inExpand
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Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells
Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood. While cyclooxygeanse-2 (COX-2) is known to be closely associated with tumor growth and metastasis inExpand
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Resveratrol Suppresses Cancer Cell Glucose Uptake by Targeting Reactive Oxygen Species–Mediated Hypoxia-Inducible Factor-1α Activation
  • K. Jung, J. Lee, +6 authors K. Lee
  • Chemistry, Medicine
  • The Journal of Nuclear Medicine
  • 1 December 2013
Resveratrol is gaining attention for its anticancer effects and is also recognized for its antioxidant properties and influence on glucose metabolism. Augmented reactive oxygen species (ROS) and highExpand
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High FDG uptake in PET/CT predicts worse prognosis in patients with metastatic gastric adenocarcinoma
PurposeWe evaluated the role of FDG-PET/CT in patients with metastatic gastric adenocarcinoma before palliative chemotherapy to predict prognosis and chemotherapeutic response.MethodsThe studyExpand
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Implementation of antiretroviral therapy adherence interventions: a realist synthesis of evidence.
AIM This paper is a report of a synthesis of evidence on implementation of interventions to improve adherence to antiretroviral therapy. BACKGROUND Evidence on efficacy must be supplemented withExpand
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Functional MR Imaging of Working Memory in the Human Brain
Objective In order to investigate the functional brain anatomy associated with verbal and visual working memory, functional magnetic resonance imaging was performed. Materials and Methods In tenExpand
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