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Translation of the shallot virus X TGB3 gene depends on non-AUG initiation and leaky scanning.
- A. Lezzhov, V. Gushchin, E. Lazareva, V. K. Vishnichenko, S. Morozov, A. Solovyev
- BiologyThe Journal of general virology
- 1 October 2015
Site-directed mutagenesis was used to demonstrate that the ShVX TGB3 could be translated on a bicistronic mRNA template via a leaky scanning mechanism, and sequence analysis was carried out to predict possible non-AUG initiator codons in the ShvX T GB3-encoding sequence.
Subcellular localization and detection of Tobacco mosaic virus ORF6 protein by immunoelectron microscopy
- T. Erokhina, E. Lazareva, K. Richert-Pöggeler, E. Sheval, A. Solovyev, S. Morozov
- BiologyBiochemistry (Moscow)
- 20 January 2017
It is shown that ORF6 peptide is accumulated after infection in case of two isolates of Tobacco mosaic virus strain U1 (TMV-U1 common and TMV- U1 isolate A15) and unlike virus particles accumulating in the cytoplasm, the product of the ORF 6 gene is found mainly in nuclei, which correlates with previously published data about transient expression of ORF8 of TMV.
Acquisition of Full-Length Viral Helicase Domains by Insect Retrotransposon-Encoded Polypeptides
- E. Lazareva, A. Lezzhov, N. Vassetzky, A. Solovyev, S. Morozov
- BiologyFront. Microbiol.
- 22 December 2015
This work describes a new example of insect R1 LINEs with an additional C-terminal domain in their open reading frame 2, similar to NTPase/helicase (SF1H) domains, which are found in replicative proteins encoded by plant viruses of the genus Tobamovirus.
Reticulon-like properties of a plant virus-encoded movement protein.
It is proposed that the induction of ER constrictions contributes to the BMB2-dependent increase in PD permeability and formation of the PD-associated replication compartments therefore facilitating the virus intercellular spread.
Complexes assembled from TMV-derived spherical particles and entire virions of heterogeneous nature
- E. Trifonova, N. Nikitin, A. Gmyl, E. Lazareva, O. Karpova, J. Atabekov
- BiologyJournal of biomolecular structure & dynamics
- 23 April 2014
It is reported that entire isometric virions of heterogeneous nature bind non-specifically to the SPs, and that immunogenicity of entire CaMV crosslinked to SP was rather low which could be due to the above-mentioned masking of theSPs booster.
Immunogenic compositions assembled from tobacco mosaic virus-generated spherical particle platforms and foreign antigens.
It is shown that SPs represent a universal particle platform that can form compositions by binding a diversity of various foreign proteins/epitopes of viral and non-viral origin to their surface.
A novel block of plant virus movement genes.
- E. Lazareva, A. Lezzhov, T. Komarova, S. Morozov, M. Heinlein, A. Solovyev
- BiologyMolecular plant pathology
- 1 June 2017
It is demonstrated that the proteins encoded by the ORF2 and ORF3 in HGSV RNA2 are necessary and sufficient to mediate cell-to-cell movement of transport-deficient Potato virus X in Nicotiana benthamiana.
RNA phloem transport mediated by pre-miRNA and viral tRNA-like structures.
Plant-specific 4/1 polypeptide interacts with an endoplasmic reticulum protein related to human BAP31
The plant-specific 4/1 protein interacts, both in yeast two-hybrid system and in vitro, and co-localizes in plant cells with plant BAP-like protein, the orthologue of human protein BAP31, the physiologically relevant concentrations of both proteins.