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Structural changes of the trabecular meshwork in different kinds of glaucoma.
The functional relationship between ciliary muscle and TM and the age-related changes in morphology of the outflow system are described first and one main finding in the ageing TM concerns changes of the elastic fiber network and the anterior elastic tendons of the CM. Expand
Transforming growth factor β2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development
PSX eyes differ from POAG and JG eyes not only by their clinical or biomicroscopic appearance, but also by their normal TGF-β2 levels in aqueous humor, which indicated that other factors are also involved in the scarring of the filtration bleb. Expand
Effects of TGF-beta2 in perfused human eyes.
The hypothesis that elevated TGF-beta2 levels in the aqueous humor play a role in the pathogenesis of the ocular hypertension in POAG is supported. Expand
The fine structure of the cribriform meshwork in normal and glaucomatous eyes as seen in tangential sections.
Electron microscopic serial sections in a tangential plane through the inner wall of Schlemm's canal and the trabecular meshwork in normal and glaucomatous eyes revealed a characteristic network ofExpand
Morphological changes in glaucomatous eyes and the role of TGFbeta2 for the pathogenesis of the disease.
This review summarizes the Ernst H. Bárány Prize Lecture given at the XVI. meeting 2004 of the International Society of Eye Research in Sydney, Australia. The article describes the author's earlyExpand
Species differences in choroidal vasodilative innervation: evidence for specific intrinsic nitrergic and VIP-positive neurons in the human eye.
The presence of an intrinsic nerve cell plexus that is specifically localized in human eyes in the temporal-central portion of the choroid indicates a functional significance of the nitrergic choroidal innervation for the fovea. Expand
Severity of Optic Nerve Damage in Eyes with POAG Is Correlated with Changes in the Trabecular Meshwork
Increasing severity of optic nerve damage in POAG is accompanied by an increase in the amount of sheath-derived plaque material in the trabecular meshwork. Expand
Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyes.
The composition of the extracellular material of the cribriform meshwork was compared in five normal and 13 glaucomatous eyes of the same age group and the fibrillar components, which partly could be studied only after enzymatic treatment, showed qualitative differences between normal and glaucolysis eyes. Expand
Morphology of the Trabecular Meshwork
It is well estabilished that in primate eyes most of the resistance to aqueous humor outflow needed for maintenance of a pressure gradient between intraocular pressure of ~ 15 mm Hg and theExpand
Transforming growth factor-beta 2 modulated extracellular matrix component expression in cultured human optic nerve head astrocytes.
TGF-beta 2 is capable of inducing the expression of ECM and basement membrane components in cultured ONH astrocytes via CTGF and upregulated TSP-1, a protein naturally involved in the activation of latent TGF- beta. Expand