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Circulating levels of leptin, adiponectin, resistin, and ghrelin in inflammatory bowel disease
TLDR
Serum levels of adiponectin, resistin, and active ghrelin are increased whereas serum levels of leptin are decreased in patients with IBD, and no association between serum adipocytokines levels and disease localization in both UC and CD patients was found. Expand
Role of Kupffer cells in the pathogenesis of liver disease.
TLDR
A model that demonstrates the role of Kupffer cells in the pathogenesis of liver disease is proposed and it is proposed that they may represent a significant source of chemoattractant molecules for cytotoxic CD8 and regulatory T cells. Expand
CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease.
TLDR
In SB immune-mediated diseases, there is repartitioning of CCR9(+) lymphocytes between SB and blood and an altered pattern of TECK expression in SB Crohn's, and the TECK/CCR9 ligand/receptor pair may play an important role in the pathogenesis of SBCrohn's disease. Expand
Mean platelet volume: a useful marker of inflammatory bowel disease activity
TLDR
Mean platelet volume is significantly reduced in active inflammatory bowel disease and is negatively correlated with the knowninflammatory bowel disease activity markers and the platelet activation products. Expand
Treatment of hepatocellular carcinoma with octreotide: a randomised controlled study
TLDR
Octreotide administration significantly improves survival and is a valuable alternative in the treatment of inoperable hepatocellular carcinoma. Expand
Diagnosing anemia in inflammatory bowel disease: beyond the established markers.
TLDR
This review discusses the newer alternative markers for iron status that may be useful when serum ferritin and Tsat are not sufficient and erythrocytes parameters like the red cell distribution width and the percentage of hypochromic red cells as well as reticulocyte parameters could be useful markers for the evaluation of anemia in IBD. Expand
Potent inhibitory action of red wine polyphenols on human breast cancer cells
TLDR
The results suggest that low concentrations of polyphenols, and consecutively, consumption of wine, or other polyphenol‐rich foods and beverages, could have a beneficial antiproliferative effect on breast cancer cell growth. Expand
Balthazar Computed Tomography Severity Index Is Superior to Ranson Criteria and APACHE II and III Scoring Systems in Predicting Acute Pancreatitis Outcome
TLDR
The Balthazar score is superior to other scoring systems in predicting acute pancreatitis severity and pancreatic necrosis, however the Ranson and APACHE scores perform slightly better with respect to organ failure prediction. Expand
Role of Appendicitis and Appendectomy in the Pathogenesis of Ulcerative Colitis: A Critical Review
TLDR
The association between appendectomy and UC has recently been the subject of intense scrutiny in the hope that it may lead to the identification of important pathogenetic mechanisms and the improvement of the understanding for the disease pathogenesis. Expand
Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation.
TLDR
The results indicate that the stilbene inhibits potently cell proliferation, reduces the production of reactive oxygen species and induces apoptosis, through cell cycle arrest in G1 and G2/M phases, and modulates the NO/NOS system, by increasing iNOS and eNOS expression, NOS activity and NO production. Expand
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