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Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search.
We present a statistical model to estimate the accuracy of peptide assignments to tandem mass (MS/MS) spectra made by database search applications such as SEQUEST. Expand
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A statistical model for identifying proteins by tandem mass spectrometry.
A statistical model is presented for computing probabilities that proteins are present in a sample on the basis of peptides assigned to tandem mass (MS/MS) spectra acquired from a proteolytic digestExpand
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Transcriptome analysis of Escherichia coli using high-density oligonucleotide probe arrays.
Microarrays traditionally have been used to analyze the expression behavior of large numbers of coding transcripts. Here we present a comprehensive approach for high-throughput transcript discoveryExpand
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Experimental protein mixture for validating tandem mass spectral analysis.
Several methods have been used to identify peptides that correspond to tandem mass spectra. In this work, we describe a data set of low energy tandem mass spectra generated from a control mixture ofExpand
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Genome Project Standards in a New Era of Sequencing
More detailed sequence standards that keep up with revolutionary sequencing technologies will aid the research community in evaluating data. For over a decade, genome sequences have adhered to onlyExpand
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Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project
The Minimum Information for Biological and Biomedical Investigations (MIBBI) project aims to foster the coordinated development of minimum-information checklists and provide a resource for those exploring the range of extant checklists. Expand
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Meeting Report: The Terabase Metagenomics Workshop and the Vision of an Earth Microbiome Project
Between July 18th and 24th 2010, 26 leading microbial ecology, computation, bioinformatics and statistics researchers came together in Snowbird, Utah (USA) to discuss the challenge of how to bestExpand
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MOPED: Model Organism Protein Expression Database
MOPED is a new and expanding proteomics resource that enables rapid browsing of protein expression information from publicly available studies on humans and model organisms. Expand
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Global profiling of Shewanella oneidensis MR-1: expression of hypothetical genes and improved functional annotations.
The gamma-proteobacterium Shewanella oneidensis strain MR-1 is a metabolically versatile organism that can reduce a wide range of organic compounds, metal ions, and radionuclides. Similar to mostExpand
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Differential stable isotope labeling of peptides for quantitation and de novo sequence derivation.
We have demonstrated the use of per-methyl esterification of peptides for relative quantification of proteins between two mixtures of proteins and automated de novo sequence derivation on the sameExpand
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