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Mutations in DDX58, which encodes RIG-I, cause atypical Singleton-Merten syndrome.
Singleton-Merten syndrome (SMS) is an autosomal-dominant multi-system disorder characterized by dental dysplasia, aortic calcification, skeletal abnormalities, glaucoma, psoriasis, and otherExpand
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mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation.
mTORC1 plays a key role in autophagy as a negative regulator. The currently known targets of mTORC1 in the autophagy pathway mainly function at early stages of autophagosome formation. Here, weExpand
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Cardiovascular manifestations of Takayasu arteritis and their relationship to the disease activity: analysis of 204 Korean patients at a single center.
Takayasu's arteritis (TA) is primary vasculitis. Cardiac involvements in TA is due to the consequences of the vascular lesions as well as the primary pathology of the heart. The disease activity ofExpand
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Overexpression of FTL1/DDF1, an AP2 transcription factor, enhances tolerance to cold, drought, and heat stresses in Arabidopsis thaliana.
Freezing temperatures control where and when plants can grow, and negatively influence crop quality and productivity. To identify key regulatory genes involved in cold adaptation, we screenedExpand
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Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study
BackgroundWe performed multicenter study to define clinical characteristics of noncutaneous melanomas and to establish prognostic factors patients who received curative resection.MethodsOf the 141Expand
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Fermented kimchi reduces body weight and improves metabolic parameters in overweight and obese patients.
Kimchi is a traditional fermented Korean food that has garnered international interest due to its various beneficial effects. Focusing on the effect of fermentation, this study hypothesized thatExpand
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Atorvastatin and Simvastatin, but not Pravastatin, Up-regulate LPS-Induced MMP-9 Expression in Macrophages by Regulating Phosphorylation of ERK and CREB
  • D. Lee, E. Park, +6 authors D. Kim
  • Medicine, Biology
  • Cellular Physiology and Biochemistry
  • 19 July 2012
Statins suppress expression of pro-inflammatory cytokines in endothelial cells, whereas they enhance it in immune cells. Pro-inflammatory cytokines and lipopolysaccharide (LPS) induce matrixExpand
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Radiologic findings of metastatic signet ring cell carcinoma to the breast from stomach.
Two Korean women (41 and 23-years of age) presented with painful breast enlargement and redness. The involved breast was confirmed as metastatic signet ring cell carcinoma. Although metastatic signetExpand
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Assessment of regional aortic stiffness with cardiac magnetic resonance imaging in a healthy Asian population
The aim of this study was to determine the normal values for aortic pulse wave velocity (PWV) and distensibility using cine and phase contrast cardiac magnetic resonance imaging (CMRI) in patientsExpand
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Ischemic Postconditioning During Primary Percutaneous Coronary Intervention: The Effects of Postconditioning on Myocardial Reperfusion in Patients With ST-Segment Elevation Myocardial Infarction
Background— Ischemic postconditioning has been reported to reduce infarct size in patients with ST-segment–elevation myocardial infarction. However, cardioprotective effects of postconditioning haveExpand
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